Genomic analysis of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) strains isolated in Malaysia
Using seven complete genomes of human SARS-CoV-2 (retrieved from GISAID) isolated in Malaysia for phylogenetic tree construction, the current study showed that these strains formed four distinct clades when compared with other representative strains from Asia, Europe and US. In light of that, the g...
Saved in:
| Main Authors: | , , , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
HH Publisher
2020-06-01
|
| Series: | Progress in Microbes and Molecular Biology |
| Online Access: | https://journals.hh-publisher.com/index.php/pmmb/article/view/301 |
| Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
| _version_ | 1832541431545200640 |
|---|---|
| author | Hooi-Leng Ser Loh Teng-Hern Tan Jodi Woan-Fei Law Vengadesh Letchumanan Nurul-Syakima Ab Mutalib Learn-Han Lee |
| author_facet | Hooi-Leng Ser Loh Teng-Hern Tan Jodi Woan-Fei Law Vengadesh Letchumanan Nurul-Syakima Ab Mutalib Learn-Han Lee |
| author_sort | Hooi-Leng Ser |
| collection | DOAJ |
| description |
Using seven complete genomes of human SARS-CoV-2 (retrieved from GISAID) isolated in Malaysia for
phylogenetic tree construction, the current study showed that these strains formed four distinct clades when compared with other representative strains from Asia, Europe and US. In light of that, the genome sequences of these strains isolated in Malaysia suggested that there is currently more than one “type” of strain within the country. Complementing with epidemiological and experimental studies, these findings allow better understanding the prevalence of certain types in Malaysia and permits further in-depth studies on the virulence and pathogenic mechanisms of these strains which is particularly critical to speed up the development of effective treatment regime.
|
| format | Article |
| id | doaj-art-b208c2b6a08c4bdfacabf57c5db922fd |
| institution | Kabale University |
| issn | 2637-1049 |
| language | English |
| publishDate | 2020-06-01 |
| publisher | HH Publisher |
| record_format | Article |
| series | Progress in Microbes and Molecular Biology |
| spelling | doaj-art-b208c2b6a08c4bdfacabf57c5db922fd2025-02-04T08:37:03ZengHH PublisherProgress in Microbes and Molecular Biology2637-10492020-06-013110.36877/pmmb.a0000093Genomic analysis of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) strains isolated in MalaysiaHooi-Leng SerLoh Teng-Hern TanJodi Woan-Fei LawVengadesh LetchumananNurul-Syakima Ab MutalibLearn-Han Lee Using seven complete genomes of human SARS-CoV-2 (retrieved from GISAID) isolated in Malaysia for phylogenetic tree construction, the current study showed that these strains formed four distinct clades when compared with other representative strains from Asia, Europe and US. In light of that, the genome sequences of these strains isolated in Malaysia suggested that there is currently more than one “type” of strain within the country. Complementing with epidemiological and experimental studies, these findings allow better understanding the prevalence of certain types in Malaysia and permits further in-depth studies on the virulence and pathogenic mechanisms of these strains which is particularly critical to speed up the development of effective treatment regime. https://journals.hh-publisher.com/index.php/pmmb/article/view/301 |
| spellingShingle | Hooi-Leng Ser Loh Teng-Hern Tan Jodi Woan-Fei Law Vengadesh Letchumanan Nurul-Syakima Ab Mutalib Learn-Han Lee Genomic analysis of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) strains isolated in Malaysia Progress in Microbes and Molecular Biology |
| title | Genomic analysis of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) strains isolated in Malaysia |
| title_full | Genomic analysis of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) strains isolated in Malaysia |
| title_fullStr | Genomic analysis of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) strains isolated in Malaysia |
| title_full_unstemmed | Genomic analysis of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) strains isolated in Malaysia |
| title_short | Genomic analysis of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) strains isolated in Malaysia |
| title_sort | genomic analysis of severe acute respiratory syndrome coronavirus 2 sars cov 2 strains isolated in malaysia |
| url | https://journals.hh-publisher.com/index.php/pmmb/article/view/301 |
| work_keys_str_mv | AT hooilengser genomicanalysisofsevereacuterespiratorysyndromecoronavirus2sarscov2strainsisolatedinmalaysia AT lohtengherntan genomicanalysisofsevereacuterespiratorysyndromecoronavirus2sarscov2strainsisolatedinmalaysia AT jodiwoanfeilaw genomicanalysisofsevereacuterespiratorysyndromecoronavirus2sarscov2strainsisolatedinmalaysia AT vengadeshletchumanan genomicanalysisofsevereacuterespiratorysyndromecoronavirus2sarscov2strainsisolatedinmalaysia AT nurulsyakimaabmutalib genomicanalysisofsevereacuterespiratorysyndromecoronavirus2sarscov2strainsisolatedinmalaysia AT learnhanlee genomicanalysisofsevereacuterespiratorysyndromecoronavirus2sarscov2strainsisolatedinmalaysia |