Evolution of SARS-CoV-2 T cell responses as a function of multiple COVID-19 boosters

Evolution of SARS-CoV-2 T cell responses as a function of multiple COVID-19 boosters

Summary: We investigate the long-term impact of repeated COVID-19 vaccinations on adaptive immunity through a 3-year study of 78 individuals without reported symptomatic infections. We observe distinct dynamics in spike-specific responses across multiple vaccine doses. While antibody levels increase...

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Bibliographic Details
Main Authors: Ricardo da Silva Antunes, Vicente Fajardo-Rosas, Esther Dawen Yu, Rosa Isela Gálvez, Adam Abawi, E. Alexandar Escarrega, Amparo Martínez-Pérez, Emil Johansson, Benjamin Goodwin, April Frazier, Jennifer M. Dan, Shane Crotty, Grégory Seumois, Daniela Weiskopf, Pandurangan Vijayanand, Alessandro Sette
Format: Article
Language:English
Published: Elsevier 2025-07-01
Series:Cell Reports
Subjects:
CP: Immunology
Online Access:http://www.sciencedirect.com/science/article/pii/S2211124725006783
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