Antioxidant Activity and Phenolics of Kabau (Archidendron bubalinum) Pod Peel Extract from East Lampung on Blood Cell Male Mice Induced by Cadmium
Cadmium (Cd) increases oxidative stress, which increases the likelihood of health problems. To protect the body from oxidative stress, natural antioxidants obtained from plants are required. The kabau plant (Archidendron bubalinum) is thought to have antioxidant phytochemicals. The purpose of this...
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| Format: | Article |
| Language: | English |
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Bogor Agricultural University
2025-03-01
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| Series: | Jurnal Ilmu Pertanian Indonesia |
| Online Access: | https://journal.ipb.ac.id/index.php/JIPI/article/view/57893 |
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| author | Elisa Nurma Riana Muhammad Eka Prastya Gian Primahana Hida Arliani Nur Anisa Iffa Afiqa Khairani Lisana Husna Imaniar |
| author_facet | Elisa Nurma Riana Muhammad Eka Prastya Gian Primahana Hida Arliani Nur Anisa Iffa Afiqa Khairani Lisana Husna Imaniar |
| author_sort | Elisa Nurma Riana |
| collection | DOAJ |
| description |
Cadmium (Cd) increases oxidative stress, which increases the likelihood of health problems. To protect the body from oxidative stress, natural antioxidants obtained from plants are required. The kabau plant (Archidendron bubalinum) is thought to have antioxidant phytochemicals. The purpose of this study was to assess the antioxidant activity and total phenolic component content of kabau pod peels, as well as their effect on the quantity of erythrocytes and leukocytes in male mice exposed to cadmium. This study used a completely randomized design, with 24 mice divided into six groups: three control groups and three treatment groups. The findings of assessing the antioxidant activity of peel extract revealed that the IC50 was 93.6 ppm, which is considered strong. The phenolic content of peel extract was 72.26 mg GAE/g. Giving pod peel extract to mice increased the number of erythrocytes and leukocytes, however the impact was not significant (p = 0.028 and P = 0.239). Mice with 380 mg/kg BW produced better outcomes.
Keywords: antioxidant, Archidendron, blood cell, kabau, phenolics
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| format | Article |
| id | doaj-art-b1fb2a14a6794c9f89ea393a41794ec5 |
| institution | DOAJ |
| issn | 0853-4217 2443-3462 |
| language | English |
| publishDate | 2025-03-01 |
| publisher | Bogor Agricultural University |
| record_format | Article |
| series | Jurnal Ilmu Pertanian Indonesia |
| spelling | doaj-art-b1fb2a14a6794c9f89ea393a41794ec52025-08-20T03:00:10ZengBogor Agricultural UniversityJurnal Ilmu Pertanian Indonesia0853-42172443-34622025-03-0130210.18343/jipi.30.2.353Antioxidant Activity and Phenolics of Kabau (Archidendron bubalinum) Pod Peel Extract from East Lampung on Blood Cell Male Mice Induced by CadmiumElisa Nurma Riana0Muhammad Eka Prastya1Gian Primahana2Hida Arliani Nur Anisa3Iffa Afiqa Khairani4Lisana Husna Imaniar5Biology Study Program, Faculty of Science, Sumatra Institute of Technology, Lampung 35365, IndonesiaResearch Center for Pharmaceutical Ingredients and Traditional Medicine, National Research, and Innovation Agency (BRIN), Tengerang 15311 IndonesiaResearch Center for Pharmaceutical Ingredients and Traditional Medicine, National Research, and Innovation Agency (BRIN), Tengerang 15311 IndonesiaBiology Study Program, Faculty of Science, Sumatra Institute of Technology, Lampung 35365, IndonesiaBiology Study Program, Faculty of Science, Sumatra Institute of Technology, Lampung 35365, IndonesiaBiology Study Program, Faculty of Science, Sumatra Institute of Technology, Lampung 35365, Indonesia Cadmium (Cd) increases oxidative stress, which increases the likelihood of health problems. To protect the body from oxidative stress, natural antioxidants obtained from plants are required. The kabau plant (Archidendron bubalinum) is thought to have antioxidant phytochemicals. The purpose of this study was to assess the antioxidant activity and total phenolic component content of kabau pod peels, as well as their effect on the quantity of erythrocytes and leukocytes in male mice exposed to cadmium. This study used a completely randomized design, with 24 mice divided into six groups: three control groups and three treatment groups. The findings of assessing the antioxidant activity of peel extract revealed that the IC50 was 93.6 ppm, which is considered strong. The phenolic content of peel extract was 72.26 mg GAE/g. Giving pod peel extract to mice increased the number of erythrocytes and leukocytes, however the impact was not significant (p = 0.028 and P = 0.239). Mice with 380 mg/kg BW produced better outcomes. Keywords: antioxidant, Archidendron, blood cell, kabau, phenolics https://journal.ipb.ac.id/index.php/JIPI/article/view/57893 |
| spellingShingle | Elisa Nurma Riana Muhammad Eka Prastya Gian Primahana Hida Arliani Nur Anisa Iffa Afiqa Khairani Lisana Husna Imaniar Antioxidant Activity and Phenolics of Kabau (Archidendron bubalinum) Pod Peel Extract from East Lampung on Blood Cell Male Mice Induced by Cadmium Jurnal Ilmu Pertanian Indonesia |
| title | Antioxidant Activity and Phenolics of Kabau (Archidendron bubalinum) Pod Peel Extract from East Lampung on Blood Cell Male Mice Induced by Cadmium |
| title_full | Antioxidant Activity and Phenolics of Kabau (Archidendron bubalinum) Pod Peel Extract from East Lampung on Blood Cell Male Mice Induced by Cadmium |
| title_fullStr | Antioxidant Activity and Phenolics of Kabau (Archidendron bubalinum) Pod Peel Extract from East Lampung on Blood Cell Male Mice Induced by Cadmium |
| title_full_unstemmed | Antioxidant Activity and Phenolics of Kabau (Archidendron bubalinum) Pod Peel Extract from East Lampung on Blood Cell Male Mice Induced by Cadmium |
| title_short | Antioxidant Activity and Phenolics of Kabau (Archidendron bubalinum) Pod Peel Extract from East Lampung on Blood Cell Male Mice Induced by Cadmium |
| title_sort | antioxidant activity and phenolics of kabau archidendron bubalinum pod peel extract from east lampung on blood cell male mice induced by cadmium |
| url | https://journal.ipb.ac.id/index.php/JIPI/article/view/57893 |
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