Optimizing enzyme inhibition analysis: precise estimation with a single inhibitor concentration
Abstract Enzyme inhibition analysis is essential in drug development and food processing, necessitating precise estimation of inhibition constants. Traditionally, these constants are estimated through experiments using multiple substrate and inhibitor concentrations, but inconsistencies across studi...
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| Main Authors: | Hyeong Jun Jang, Yun Min Song, Jang Su Jeon, Hwi-yeol Yun, Sang Kyum Kim, Jae Kyoung Kim |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Nature Portfolio
2025-06-01
|
| Series: | Nature Communications |
| Online Access: | https://doi.org/10.1038/s41467-025-60468-z |
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