Plasmacytoid urothelial carcinoma with duodenal metastasis—A rare tumor with unusual site of metastasis with grim outcome
Plasmacytoid urothelial carcinoma (PUC) is a newly recognized rare variant of urothelial carcinoma, which is now being increasingly diagnosed prospectively as well as by retrospective analysis of cases with a poor prognosis. Morphologically, these tumors simulate plasma cell neoplasms and pose a dia...
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Wolters Kluwer Medknow Publications
2023-01-01
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Series: | Indian Journal of Pathology and Microbiology |
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Online Access: | https://journals.lww.com/10.4103/ijpm.ijpm_840_21 |
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author | Aparna Chenniappan Norton S. Stephen Bheemanathi H. Srinivas Sreerag K. Sreenivasan Ramkumar Govindarajalou |
author_facet | Aparna Chenniappan Norton S. Stephen Bheemanathi H. Srinivas Sreerag K. Sreenivasan Ramkumar Govindarajalou |
author_sort | Aparna Chenniappan |
collection | DOAJ |
description | Plasmacytoid urothelial carcinoma (PUC) is a newly recognized rare variant of urothelial carcinoma, which is now being increasingly diagnosed prospectively as well as by retrospective analysis of cases with a poor prognosis. Morphologically, these tumors simulate plasma cell neoplasms and pose a diagnostic challenge. Identifying this variant is essential in two aspects: therapy and prognosis. Here, we present a case who underwent multiple transurethral resection of bladder tumor (TURBT) procedures, each with a diagnosis of urothelial carcinoma, the plasmacytoid type which was confirmed on radical cystectomy, and after 1 year, the patient presented with duodenal metastasis. We discuss the morphological aspects of differentiating this tumor from variants of urothelial carcinoma and other tumors with a plasmacytoid appearance. Despite the recognition and aggressive treatment, the patient expires within 2 years of the first diagnosis of bladder carcinoma. |
format | Article |
id | doaj-art-b1d0bf4cc0c24915be3da851c66bdc1c |
institution | Kabale University |
issn | 0377-4929 0974-5130 |
language | English |
publishDate | 2023-01-01 |
publisher | Wolters Kluwer Medknow Publications |
record_format | Article |
series | Indian Journal of Pathology and Microbiology |
spelling | doaj-art-b1d0bf4cc0c24915be3da851c66bdc1c2025-01-22T15:13:47ZengWolters Kluwer Medknow PublicationsIndian Journal of Pathology and Microbiology0377-49290974-51302023-01-0167117517710.4103/ijpm.ijpm_840_21Plasmacytoid urothelial carcinoma with duodenal metastasis—A rare tumor with unusual site of metastasis with grim outcomeAparna ChenniappanNorton S. StephenBheemanathi H. SrinivasSreerag K. SreenivasanRamkumar GovindarajalouPlasmacytoid urothelial carcinoma (PUC) is a newly recognized rare variant of urothelial carcinoma, which is now being increasingly diagnosed prospectively as well as by retrospective analysis of cases with a poor prognosis. Morphologically, these tumors simulate plasma cell neoplasms and pose a diagnostic challenge. Identifying this variant is essential in two aspects: therapy and prognosis. Here, we present a case who underwent multiple transurethral resection of bladder tumor (TURBT) procedures, each with a diagnosis of urothelial carcinoma, the plasmacytoid type which was confirmed on radical cystectomy, and after 1 year, the patient presented with duodenal metastasis. We discuss the morphological aspects of differentiating this tumor from variants of urothelial carcinoma and other tumors with a plasmacytoid appearance. Despite the recognition and aggressive treatment, the patient expires within 2 years of the first diagnosis of bladder carcinoma.https://journals.lww.com/10.4103/ijpm.ijpm_840_21duodenal metastasisplasmacytoidurothelial carcinoma |
spellingShingle | Aparna Chenniappan Norton S. Stephen Bheemanathi H. Srinivas Sreerag K. Sreenivasan Ramkumar Govindarajalou Plasmacytoid urothelial carcinoma with duodenal metastasis—A rare tumor with unusual site of metastasis with grim outcome Indian Journal of Pathology and Microbiology duodenal metastasis plasmacytoid urothelial carcinoma |
title | Plasmacytoid urothelial carcinoma with duodenal metastasis—A rare tumor with unusual site of metastasis with grim outcome |
title_full | Plasmacytoid urothelial carcinoma with duodenal metastasis—A rare tumor with unusual site of metastasis with grim outcome |
title_fullStr | Plasmacytoid urothelial carcinoma with duodenal metastasis—A rare tumor with unusual site of metastasis with grim outcome |
title_full_unstemmed | Plasmacytoid urothelial carcinoma with duodenal metastasis—A rare tumor with unusual site of metastasis with grim outcome |
title_short | Plasmacytoid urothelial carcinoma with duodenal metastasis—A rare tumor with unusual site of metastasis with grim outcome |
title_sort | plasmacytoid urothelial carcinoma with duodenal metastasis a rare tumor with unusual site of metastasis with grim outcome |
topic | duodenal metastasis plasmacytoid urothelial carcinoma |
url | https://journals.lww.com/10.4103/ijpm.ijpm_840_21 |
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