Topical Microbicides for the Prevention of Sexually Transmitted Diseases and HIV

The development of novel compounds to reduce the sexual transmission of human immunodeficiency virus (HIV), herpes and other pathogens causing sexually transmitted diseases (STDs) has become a topic of great interest. Condom use is the only readily available measure to reduce successfully the propag...

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Main Authors: André Désormeaux, Rabeea F Omar, Michel G Bergeron
Format: Article
Language:English
Published: Wiley 1999-01-01
Series:Canadian Journal of Infectious Diseases
Online Access:http://dx.doi.org/10.1155/1999/932936
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author André Désormeaux
Rabeea F Omar
Michel G Bergeron
author_facet André Désormeaux
Rabeea F Omar
Michel G Bergeron
author_sort André Désormeaux
collection DOAJ
description The development of novel compounds to reduce the sexual transmission of human immunodeficiency virus (HIV), herpes and other pathogens causing sexually transmitted diseases (STDs) has become a topic of great interest. Condom use is the only readily available measure to reduce successfully the propagation of these infectious agents. To reduce significantly the probability of acquiring infection, condoms should be used during all risky sexual intercourse. More attention is being given to female-controlled methods for the prevention of HIV infection because many women are unable to negotiate condom use with their sexual partners. The development of topical microbicides constitutes one of the most priori tized research areas in the field of prevention of STDs/HIV for the World Health Organization, the National Institutes of Health and the Centers for Disease Control and Prevention. Because the number of women infected with HIV, herpes and other pathogens causing STDs is growing dramatically worldwide, there is an urgent need to develop innovative preventive measures that can reduce the transmission of these pathogens with minimal mucosa! irritation, and minimal effects on the vaginal flora and pH. Some of the existing products as well as promising new topical microbicicles for the prevention of sexually transmitted infections are reviewed.
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spelling doaj-art-b1c34924efab4c27ab24b4dde64f99a12025-02-03T05:50:53ZengWileyCanadian Journal of Infectious Diseases1180-23321999-01-0110Suppl C41C48C10.1155/1999/932936Topical Microbicides for the Prevention of Sexually Transmitted Diseases and HIVAndré Désormeaux0Rabeea F Omar1Michel G Bergeron2Centre de Recherche en Infectiologie, Université Laval, Ste-Foy, Québec, CanadaCentre de Recherche en Infectiologie, Université Laval, Ste-Foy, Québec, CanadaCentre de Recherche en Infectiologie, Université Laval, Ste-Foy, Québec, CanadaThe development of novel compounds to reduce the sexual transmission of human immunodeficiency virus (HIV), herpes and other pathogens causing sexually transmitted diseases (STDs) has become a topic of great interest. Condom use is the only readily available measure to reduce successfully the propagation of these infectious agents. To reduce significantly the probability of acquiring infection, condoms should be used during all risky sexual intercourse. More attention is being given to female-controlled methods for the prevention of HIV infection because many women are unable to negotiate condom use with their sexual partners. The development of topical microbicides constitutes one of the most priori tized research areas in the field of prevention of STDs/HIV for the World Health Organization, the National Institutes of Health and the Centers for Disease Control and Prevention. Because the number of women infected with HIV, herpes and other pathogens causing STDs is growing dramatically worldwide, there is an urgent need to develop innovative preventive measures that can reduce the transmission of these pathogens with minimal mucosa! irritation, and minimal effects on the vaginal flora and pH. Some of the existing products as well as promising new topical microbicicles for the prevention of sexually transmitted infections are reviewed.http://dx.doi.org/10.1155/1999/932936
spellingShingle André Désormeaux
Rabeea F Omar
Michel G Bergeron
Topical Microbicides for the Prevention of Sexually Transmitted Diseases and HIV
Canadian Journal of Infectious Diseases
title Topical Microbicides for the Prevention of Sexually Transmitted Diseases and HIV
title_full Topical Microbicides for the Prevention of Sexually Transmitted Diseases and HIV
title_fullStr Topical Microbicides for the Prevention of Sexually Transmitted Diseases and HIV
title_full_unstemmed Topical Microbicides for the Prevention of Sexually Transmitted Diseases and HIV
title_short Topical Microbicides for the Prevention of Sexually Transmitted Diseases and HIV
title_sort topical microbicides for the prevention of sexually transmitted diseases and hiv
url http://dx.doi.org/10.1155/1999/932936
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