Young Kidney-Transplant Recipient Woman with Recurrent Urinary Tract Infection and Graft Rejection: A Case Repor

Urinary tract infection (UTI), especially recurrent UTI, is a common problem, occurring in >75% of kidney transplant recipients. Urinary tract infection (UTI) can reduce the quality of life, graft potential, and patient survival. Urosepsis with impairment of graft function is potential long-term...

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Main Authors: Nursamsu, Muhammad Reza Febriliant
Format: Article
Language:Indonesian
Published: Department of Internal Medicine, Faculty of Medicine Universitas Indonesia 2019-12-01
Series:Jurnal Penyakit Dalam Indonesia
Subjects:
Online Access:http://jurnalpenyakitdalam.ui.ac.id/index.php/jpdi/article/view/245/212
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author Nursamsu
Muhammad Reza Febriliant
author_facet Nursamsu
Muhammad Reza Febriliant
author_sort Nursamsu
collection DOAJ
description Urinary tract infection (UTI), especially recurrent UTI, is a common problem, occurring in >75% of kidney transplant recipients. Urinary tract infection (UTI) can reduce the quality of life, graft potential, and patient survival. Urosepsis with impairment of graft function is potential long-term sequelae of recurrent UTI in kidney transplantation recipients. We present a case of UTI that developed within a month after renal transplant. The patient got a urinary tract infection repeatedly. We suspect lack of hygiene as the cause of urinary tract infection, the patient was rarely cleaning-up, took a bath, changing clothes, and did not wash after urinating. But, after we did some interventions, the patient still had urinary tract infection. Laboratory findings showed decreasing of renal function since one month before. Urine culture result showed that the cause of infection was Klebsiella pneumonia. Uroflowmetry result showed post void residual about 50-60 cc. We suspected anatomy anomaly at the urinary tract of this patient. To evaluate the renal graft without biopsy, we conducted an MRI and found a pyelonephritis renal graft. We got increasing CMV antibody for opportunistic infection. The last, renal biopsy result was acute cellular rejection. After giving appropriate treatment with ganciclovir 1 x 250 mg up to 6 months and cotrimoxazole 1 x 960 mg for 14 days, the renal function still decreased and so did the urine output, then the patient fell down into graft rejection
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language Indonesian
publishDate 2019-12-01
publisher Department of Internal Medicine, Faculty of Medicine Universitas Indonesia
record_format Article
series Jurnal Penyakit Dalam Indonesia
spelling doaj-art-b1c0441edb78470dbf348f8fc129a1f52025-08-20T02:01:09ZindDepartment of Internal Medicine, Faculty of Medicine Universitas IndonesiaJurnal Penyakit Dalam Indonesia2406-89692549-06212019-12-0164204209http://dx.doi.org/10.7454/jpdi.v6i4.245Young Kidney-Transplant Recipient Woman with Recurrent Urinary Tract Infection and Graft Rejection: A Case ReporNursamsu0Muhammad Reza Febriliant1Divisi Nefrologi dan Hipertensi Ilmu Penyakit Dalam Fakultas Kedokteran Universitas Brawijaya, Malang Indonesia Brawijaya Universitiy Indonesia Urinary tract infection (UTI), especially recurrent UTI, is a common problem, occurring in >75% of kidney transplant recipients. Urinary tract infection (UTI) can reduce the quality of life, graft potential, and patient survival. Urosepsis with impairment of graft function is potential long-term sequelae of recurrent UTI in kidney transplantation recipients. We present a case of UTI that developed within a month after renal transplant. The patient got a urinary tract infection repeatedly. We suspect lack of hygiene as the cause of urinary tract infection, the patient was rarely cleaning-up, took a bath, changing clothes, and did not wash after urinating. But, after we did some interventions, the patient still had urinary tract infection. Laboratory findings showed decreasing of renal function since one month before. Urine culture result showed that the cause of infection was Klebsiella pneumonia. Uroflowmetry result showed post void residual about 50-60 cc. We suspected anatomy anomaly at the urinary tract of this patient. To evaluate the renal graft without biopsy, we conducted an MRI and found a pyelonephritis renal graft. We got increasing CMV antibody for opportunistic infection. The last, renal biopsy result was acute cellular rejection. After giving appropriate treatment with ganciclovir 1 x 250 mg up to 6 months and cotrimoxazole 1 x 960 mg for 14 days, the renal function still decreased and so did the urine output, then the patient fell down into graft rejectionhttp://jurnalpenyakitdalam.ui.ac.id/index.php/jpdi/article/view/245/212cmvgraft rejectionkidney transplanturinary tract infection
spellingShingle Nursamsu
Muhammad Reza Febriliant
Young Kidney-Transplant Recipient Woman with Recurrent Urinary Tract Infection and Graft Rejection: A Case Repor
Jurnal Penyakit Dalam Indonesia
cmv
graft rejection
kidney transplant
urinary tract infection
title Young Kidney-Transplant Recipient Woman with Recurrent Urinary Tract Infection and Graft Rejection: A Case Repor
title_full Young Kidney-Transplant Recipient Woman with Recurrent Urinary Tract Infection and Graft Rejection: A Case Repor
title_fullStr Young Kidney-Transplant Recipient Woman with Recurrent Urinary Tract Infection and Graft Rejection: A Case Repor
title_full_unstemmed Young Kidney-Transplant Recipient Woman with Recurrent Urinary Tract Infection and Graft Rejection: A Case Repor
title_short Young Kidney-Transplant Recipient Woman with Recurrent Urinary Tract Infection and Graft Rejection: A Case Repor
title_sort young kidney transplant recipient woman with recurrent urinary tract infection and graft rejection a case repor
topic cmv
graft rejection
kidney transplant
urinary tract infection
url http://jurnalpenyakitdalam.ui.ac.id/index.php/jpdi/article/view/245/212
work_keys_str_mv AT nursamsu youngkidneytransplantrecipientwomanwithrecurrenturinarytractinfectionandgraftrejectionacaserepor
AT muhammadrezafebriliant youngkidneytransplantrecipientwomanwithrecurrenturinarytractinfectionandgraftrejectionacaserepor