Phytosynthesis of Titanium Dioxide Nanoparticles Using King of Bitter Andrographis paniculata and Its Embryonic Toxicology Evaluation and Biomedical Potential

Phytosynthesis particles are the efficient activity of biomedical and environmental. In this present study, the green synthesis of titanium dioxide (TiO2) nanoparticles using the king of bitter herbal plant Andrographis paniculata was synthesized and characterized using XRD, SEM, HRTEM, AFM, and ant...

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Main Authors: S. Rajeshkumar, J. Santhoshkumar, Leta Tesfaye Jule, Krishnaraj Ramaswamy
Format: Article
Language:English
Published: Wiley 2021-01-01
Series:Bioinorganic Chemistry and Applications
Online Access:http://dx.doi.org/10.1155/2021/6267634
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author S. Rajeshkumar
J. Santhoshkumar
Leta Tesfaye Jule
Krishnaraj Ramaswamy
author_facet S. Rajeshkumar
J. Santhoshkumar
Leta Tesfaye Jule
Krishnaraj Ramaswamy
author_sort S. Rajeshkumar
collection DOAJ
description Phytosynthesis particles are the efficient activity of biomedical and environmental. In this present study, the green synthesis of titanium dioxide (TiO2) nanoparticles using the king of bitter herbal plant Andrographis paniculata was synthesized and characterized using XRD, SEM, HRTEM, AFM, and antimicrobial, antioxidant, and antidiabetic activities. The size of the particles HRTEM shows 50 nm, and SEM shows the spherical shape, which reveals the synthesis of TiO2 nanoparticles. XRD spectrum shows crystallinity of nanoparticles, and an average size is calculated about 22.97 nm. The phytosynthesis TiO2 shows the antioxidant and antidiabetic activities. Similarly, toxicity studies have demonstrated the hatching and viability LD 50 value of TiO2 250 μg/L. The current study’s findings suggested that phytosynthesis TiO2 using extract of Andrographis paniculata exposure to potential hazard factors to biomedical and environmental uses.
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institution Kabale University
issn 1565-3633
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language English
publishDate 2021-01-01
publisher Wiley
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series Bioinorganic Chemistry and Applications
spelling doaj-art-b1af6c2bb46347669cd251688a3de6d82025-02-03T01:27:24ZengWileyBioinorganic Chemistry and Applications1565-36331687-479X2021-01-01202110.1155/2021/62676346267634Phytosynthesis of Titanium Dioxide Nanoparticles Using King of Bitter Andrographis paniculata and Its Embryonic Toxicology Evaluation and Biomedical PotentialS. Rajeshkumar0J. Santhoshkumar1Leta Tesfaye Jule2Krishnaraj Ramaswamy3Nanobiomedicine Lab, Department of Pharmacology, Saveetha Dental College and Hospital, SIMATS, Chennai 600077, TN, IndiaNanobiomedicine Lab, Department of Pharmacology, Saveetha Dental College and Hospital, SIMATS, Chennai 600077, TN, IndiaDepartment of Physics, College of Natural and Computational Science, Dambi Dollo University, Dambi Dollo, EthiopiaCentre for Excellence-Indigenous Knowledge Innovative Technology Transfer and Entrepreneurship, Dambi Dollo University, Dambi Dollo, EthiopiaPhytosynthesis particles are the efficient activity of biomedical and environmental. In this present study, the green synthesis of titanium dioxide (TiO2) nanoparticles using the king of bitter herbal plant Andrographis paniculata was synthesized and characterized using XRD, SEM, HRTEM, AFM, and antimicrobial, antioxidant, and antidiabetic activities. The size of the particles HRTEM shows 50 nm, and SEM shows the spherical shape, which reveals the synthesis of TiO2 nanoparticles. XRD spectrum shows crystallinity of nanoparticles, and an average size is calculated about 22.97 nm. The phytosynthesis TiO2 shows the antioxidant and antidiabetic activities. Similarly, toxicity studies have demonstrated the hatching and viability LD 50 value of TiO2 250 μg/L. The current study’s findings suggested that phytosynthesis TiO2 using extract of Andrographis paniculata exposure to potential hazard factors to biomedical and environmental uses.http://dx.doi.org/10.1155/2021/6267634
spellingShingle S. Rajeshkumar
J. Santhoshkumar
Leta Tesfaye Jule
Krishnaraj Ramaswamy
Phytosynthesis of Titanium Dioxide Nanoparticles Using King of Bitter Andrographis paniculata and Its Embryonic Toxicology Evaluation and Biomedical Potential
Bioinorganic Chemistry and Applications
title Phytosynthesis of Titanium Dioxide Nanoparticles Using King of Bitter Andrographis paniculata and Its Embryonic Toxicology Evaluation and Biomedical Potential
title_full Phytosynthesis of Titanium Dioxide Nanoparticles Using King of Bitter Andrographis paniculata and Its Embryonic Toxicology Evaluation and Biomedical Potential
title_fullStr Phytosynthesis of Titanium Dioxide Nanoparticles Using King of Bitter Andrographis paniculata and Its Embryonic Toxicology Evaluation and Biomedical Potential
title_full_unstemmed Phytosynthesis of Titanium Dioxide Nanoparticles Using King of Bitter Andrographis paniculata and Its Embryonic Toxicology Evaluation and Biomedical Potential
title_short Phytosynthesis of Titanium Dioxide Nanoparticles Using King of Bitter Andrographis paniculata and Its Embryonic Toxicology Evaluation and Biomedical Potential
title_sort phytosynthesis of titanium dioxide nanoparticles using king of bitter andrographis paniculata and its embryonic toxicology evaluation and biomedical potential
url http://dx.doi.org/10.1155/2021/6267634
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