Can social adversity and mental, physical and oral multimorbidity form a syndemic? A concept and protocol paper

BackgroundClustering mental, physical and oral conditions reduce drastically the life expectancy. These conditions are precipitated and perpetuated by adverse social, economic, environmental, political and healthcare contextual factors, and sustained through bidirectional interactions forming potent...

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Main Authors: Easter Joury, Eliana Nakhleh, Ed Beveridge, Derek Tracy, Ellie Heidari, David Shiers, Silke Vereeken, Emily Peckham, Simon Gilbody, Jayati Das-Munshi, Farida Fortune, Vishal R. Aggarwal, Masuma Mishu, Joseph Firth, Kamaldeep Bhui
Format: Article
Language:English
Published: Frontiers Media S.A. 2025-01-01
Series:Frontiers in Psychiatry
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Online Access:https://www.frontiersin.org/articles/10.3389/fpsyt.2024.1426054/full
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author Easter Joury
Easter Joury
Eliana Nakhleh
Ed Beveridge
Derek Tracy
Derek Tracy
Derek Tracy
Derek Tracy
Ellie Heidari
Ellie Heidari
David Shiers
David Shiers
David Shiers
Silke Vereeken
Emily Peckham
Simon Gilbody
Simon Gilbody
Jayati Das-Munshi
Farida Fortune
Farida Fortune
Vishal R. Aggarwal
Masuma Mishu
Masuma Mishu
Joseph Firth
Joseph Firth
Kamaldeep Bhui
Kamaldeep Bhui
Kamaldeep Bhui
Kamaldeep Bhui
author_facet Easter Joury
Easter Joury
Eliana Nakhleh
Ed Beveridge
Derek Tracy
Derek Tracy
Derek Tracy
Derek Tracy
Ellie Heidari
Ellie Heidari
David Shiers
David Shiers
David Shiers
Silke Vereeken
Emily Peckham
Simon Gilbody
Simon Gilbody
Jayati Das-Munshi
Farida Fortune
Farida Fortune
Vishal R. Aggarwal
Masuma Mishu
Masuma Mishu
Joseph Firth
Joseph Firth
Kamaldeep Bhui
Kamaldeep Bhui
Kamaldeep Bhui
Kamaldeep Bhui
author_sort Easter Joury
collection DOAJ
description BackgroundClustering mental, physical and oral conditions reduce drastically the life expectancy. These conditions are precipitated and perpetuated by adverse social, economic, environmental, political and healthcare contextual factors, and sustained through bidirectional interactions forming potentially a ‘syndemic’. No previous study has investigated such potential syndemic. Thus, the present project aimed to (i) test for syndemic interactions between social adversity (socioeconomic adversity and traumatic events) and mental, physical and oral multimorbidity using the syndemic theoretical framework; and (ii) determine whether the syndemic relationships vary by age, sex and ethnicity.MethodsData from three large-scale population-based databases: UK BioBank, US National Health and Nutrition Examination Survey (NHANES) and the Research with East London Adolescents Community Health Survey (RELACHS) will be analysed. Structural equation modelling (SEM) will be utilised to conceptualise syndemic factors and model complex relationships between directly observed and indirectly observed (latent) variables (syndemic constructs).Discussionthe syndemic conceptualisation provides a valuable framework to understand health and illness, and hence to better design and deliver effective and cost-effective preventative and curative integrated (syndemic) care to improve patient and population health. Such syndemic care aims to address the social determinants of health, whilst simultaneously managing all interlocked conditions.
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spelling doaj-art-b1a609ebc4f745ed818b270c165a75512025-01-23T07:59:31ZengFrontiers Media S.A.Frontiers in Psychiatry1664-06402025-01-011510.3389/fpsyt.2024.14260541426054Can social adversity and mental, physical and oral multimorbidity form a syndemic? A concept and protocol paperEaster Joury0Easter Joury1Eliana Nakhleh2Ed Beveridge3Derek Tracy4Derek Tracy5Derek Tracy6Derek Tracy7Ellie Heidari8Ellie Heidari9David Shiers10David Shiers11David Shiers12Silke Vereeken13Emily Peckham14Simon Gilbody15Simon Gilbody16Jayati Das-Munshi17Farida Fortune18Farida Fortune19Vishal R. Aggarwal20Masuma Mishu21Masuma Mishu22Joseph Firth23Joseph Firth24Kamaldeep Bhui25Kamaldeep Bhui26Kamaldeep Bhui27Kamaldeep Bhui28Centre for Dental Public Health and Primary Care, Barts and the London School of Medicine and Dentistry, Queen Mary University of London, London, United KingdomBarts Health National Health Service (NHS) Trust, London, United KingdomHomerton College, University of Cambridge, Cambridge, United KingdomUCLPartners, London, United KingdomWest London National Health Service (NHS) Trust, London, United KingdomBrunel University Medical School, London, United KingdomDepartment of Psychosis Studies, Institute of Psychiatry, Psychology and Neuroscience, King’s College London, London, United KingdomDivision of Psychiatry, Department of Brain Sciences, Imperial College London, London, United KingdomFaculty of Dentistry, Oral & Craniofacial Sciences King’ College London, London, United Kingdom0Department of Sedation and Special Care Dentistry, Guy’s Hospital, London, United Kingdom1Greater Manchester Mental Health National Health Service (NHS) Foundation Trust, Manchester, United Kingdom2Early Psychosis Unit, University of Manchester, Manchester, United Kingdom3University of Keele, Staffordshire, United Kingdom4Department of Health Sciences, Hull York Medical School, University of York, York, United Kingdom5School of Health Sciences, Bangor University, Gwynedd, United Kingdom4Department of Health Sciences, Hull York Medical School, University of York, York, United Kingdom6Hull York Medical School, University of York, York, United Kingdom7Department of Psychological Medicine, Institute of Psychiatry, Psychology, and Neuroscience, King’s College London, London, United Kingdom8Centre for Clinical and Diagnostic Oral Sciences, Barts and the London School of Medicine and Dentistry, Queen Mary University of London, London, United Kingdom9London Behçet’s Centre, Barts Health London, London, United Kingdom0School of Dentistry, University of Leeds, Leeds, United Kingdom4Department of Health Sciences, Hull York Medical School, University of York, York, United Kingdom1Institute of Epidemiology and Health Care, University College London, London, United Kingdom2Division of Psychology and Mental Health, University of Manchester, Manchester Academic Health Science Centre, Manchester, United Kingdom3Greater Manchester Mental Health National Health Service (NHS) Foundation Trust, Manchester Academic Health Science Centre, Manchester, United Kingdom4Department of Psychiatry, Nuffield Department of Primary Care Health Science, University of Oxford, Oxford, United Kingdom5Wadham College, University of Oxford, Oxford, United Kingdom6East London and Oxford Health National Health Service (NHS) Foundation Trusts, London, United Kingdom7World Psychiatric Association (WPA) Collaborating Centre Oxford, Oxford, United KingdomBackgroundClustering mental, physical and oral conditions reduce drastically the life expectancy. These conditions are precipitated and perpetuated by adverse social, economic, environmental, political and healthcare contextual factors, and sustained through bidirectional interactions forming potentially a ‘syndemic’. No previous study has investigated such potential syndemic. Thus, the present project aimed to (i) test for syndemic interactions between social adversity (socioeconomic adversity and traumatic events) and mental, physical and oral multimorbidity using the syndemic theoretical framework; and (ii) determine whether the syndemic relationships vary by age, sex and ethnicity.MethodsData from three large-scale population-based databases: UK BioBank, US National Health and Nutrition Examination Survey (NHANES) and the Research with East London Adolescents Community Health Survey (RELACHS) will be analysed. Structural equation modelling (SEM) will be utilised to conceptualise syndemic factors and model complex relationships between directly observed and indirectly observed (latent) variables (syndemic constructs).Discussionthe syndemic conceptualisation provides a valuable framework to understand health and illness, and hence to better design and deliver effective and cost-effective preventative and curative integrated (syndemic) care to improve patient and population health. Such syndemic care aims to address the social determinants of health, whilst simultaneously managing all interlocked conditions.https://www.frontiersin.org/articles/10.3389/fpsyt.2024.1426054/fullmental disordersphysical conditionsdental diseasessyndemicsconceptualisationmethodology
spellingShingle Easter Joury
Easter Joury
Eliana Nakhleh
Ed Beveridge
Derek Tracy
Derek Tracy
Derek Tracy
Derek Tracy
Ellie Heidari
Ellie Heidari
David Shiers
David Shiers
David Shiers
Silke Vereeken
Emily Peckham
Simon Gilbody
Simon Gilbody
Jayati Das-Munshi
Farida Fortune
Farida Fortune
Vishal R. Aggarwal
Masuma Mishu
Masuma Mishu
Joseph Firth
Joseph Firth
Kamaldeep Bhui
Kamaldeep Bhui
Kamaldeep Bhui
Kamaldeep Bhui
Can social adversity and mental, physical and oral multimorbidity form a syndemic? A concept and protocol paper
Frontiers in Psychiatry
mental disorders
physical conditions
dental diseases
syndemics
conceptualisation
methodology
title Can social adversity and mental, physical and oral multimorbidity form a syndemic? A concept and protocol paper
title_full Can social adversity and mental, physical and oral multimorbidity form a syndemic? A concept and protocol paper
title_fullStr Can social adversity and mental, physical and oral multimorbidity form a syndemic? A concept and protocol paper
title_full_unstemmed Can social adversity and mental, physical and oral multimorbidity form a syndemic? A concept and protocol paper
title_short Can social adversity and mental, physical and oral multimorbidity form a syndemic? A concept and protocol paper
title_sort can social adversity and mental physical and oral multimorbidity form a syndemic a concept and protocol paper
topic mental disorders
physical conditions
dental diseases
syndemics
conceptualisation
methodology
url https://www.frontiersin.org/articles/10.3389/fpsyt.2024.1426054/full
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