Conserved glucokinase regulation in zebrafish confirms therapeutic utility for pharmacologic modulation in diabetes

Abstract Glucokinase (GCK) is an essential enzyme for blood glucose homeostasis. Because of its importance in glucose metabolism, GCK is considered an attractive target for the development of antidiabetic drugs. However, a viable therapeutic agent has still to emerge, prompting efforts to improve un...

Full description

Saved in:
Bibliographic Details
Main Authors: Nicole Schmitner, Sophie Thumer, Dominik Regele, Elena Mayer, Ines Bergerweiss, Christian Helker, Didier Y. R. Stainier, Dirk Meyer, Robin A. Kimmel
Format: Article
Language:English
Published: Nature Portfolio 2024-11-01
Series:Communications Biology
Online Access:https://doi.org/10.1038/s42003-024-07264-5
Tags: Add Tag
No Tags, Be the first to tag this record!