A Role for Bcl-2 in Notch1-Dependent Transcription in Thymic Lymphoma Cells

A Role for Bcl-2 in Notch1-Dependent Transcription in Thymic Lymphoma Cells

Notch1 is a transcription factor important for T-cell development. Notch1 is active in double negative (DN) thymocytes, while being depressed in double positive (DP) thymocytes. Synchronously, the expression of Bcl-2 becomes downregulated during the transition from DN to DP thymocytes. We previously...

Full description

Saved in:
Bibliographic Details
Main Authors: Ronit Vogt Sionov, Shlomit Kfir-Erenfeld, Rachel Spokoini, Eitan Yefenof
Format: Article
Language:English
Published: Wiley 2012-01-01
Series:Advances in Hematology
Online Access:http://dx.doi.org/10.1155/2012/435241
Tags: Add Tag
No Tags, Be the first to tag this record!

Similar Items

Similar Items