The Influence of Occupational Factors on Contact Dermatitis in Symptomatic Healthcare Workers: A Patch Test Study

Healthcare workers (HCWs) are frequently exposed to a variety of chemical agents, which can result in the development of allergic or irritant contact dermatitis. The present study aimed to assess the prevalence of skin sensitization among HCWs who presented with symptoms of contact dermatitis, consi...

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Main Authors: Cristiana Ferrari, Giuseppina Somma, Viola Giovinazzo, Margherita Iarossi, Michele Treglia, Margherita Pallocci, Luca Di Giampaolo, Andrea Magrini, Luca Coppeta
Format: Article
Language:English
Published: MDPI AG 2025-03-01
Series:Diseases
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Online Access:https://www.mdpi.com/2079-9721/13/3/77
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author Cristiana Ferrari
Giuseppina Somma
Viola Giovinazzo
Margherita Iarossi
Michele Treglia
Margherita Pallocci
Luca Di Giampaolo
Andrea Magrini
Luca Coppeta
author_facet Cristiana Ferrari
Giuseppina Somma
Viola Giovinazzo
Margherita Iarossi
Michele Treglia
Margherita Pallocci
Luca Di Giampaolo
Andrea Magrini
Luca Coppeta
author_sort Cristiana Ferrari
collection DOAJ
description Healthcare workers (HCWs) are frequently exposed to a variety of chemical agents, which can result in the development of allergic or irritant contact dermatitis. The present study aimed to assess the prevalence of skin sensitization among HCWs who presented with symptoms of contact dermatitis, considering both occupational and non-occupational risk factors. The study population comprised 127 HCWs who attended routine occupational health surveillance at the Tor Vergata Teaching Hospital in Rome between November 2023 and May 2024. A structured dermatitis questionnaire and patch testing were administered to the participants. Demographic and lifestyle data, including information on occupation, night shift work, smoking habits, and body mass index (BMI), were collected. Patch test positivity was observed in 31.5% of participants, with the most common clinical presentation being erythematous-desquamative allergic contact dermatitis. A significantly higher likelihood of patch test positivity was observed among nurses (57.1%), particularly for nickel sensitization, compared to other occupational groups. A trend towards an association between night shift work and skin sensitization was observed, although this did not reach statistical significance. No significant associations were found for ages over 35 years, sex, or BMI. These findings highlight the elevated risk of contact sensitization among nurses, emphasizing the need for targeted interventions, including exposure reduction strategies and protective measures, to mitigate occupational skin hazards in healthcare settings.
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spelling doaj-art-b189c6081ca1462d82aca077dc170d9a2025-08-20T03:43:15ZengMDPI AGDiseases2079-97212025-03-011337710.3390/diseases13030077The Influence of Occupational Factors on Contact Dermatitis in Symptomatic Healthcare Workers: A Patch Test StudyCristiana Ferrari0Giuseppina Somma1Viola Giovinazzo2Margherita Iarossi3Michele Treglia4Margherita Pallocci5Luca Di Giampaolo6Andrea Magrini7Luca Coppeta8Department of Biomedicine and Prevention, University of Rome Tor Vergata, 00133 Rome, ItalyDepartment of Biomedicine and Prevention, University of Rome Tor Vergata, 00133 Rome, ItalyDepartment of Biomedicine and Prevention, University of Rome Tor Vergata, 00133 Rome, ItalyDepartment of Biomedicine and Prevention, University of Rome Tor Vergata, 00133 Rome, ItalyDepartment of Biomedicine and Prevention, University of Rome Tor Vergata, 00133 Rome, ItalyDepartment of Biomedicine and Prevention, University of Rome Tor Vergata, 00133 Rome, ItalyDepartment of Occupational Medicine, University of Chieti “G. D’Annunzio”, 66013 Chieti, ItalyDepartment of Biomedicine and Prevention, University of Rome Tor Vergata, 00133 Rome, ItalyDepartment of Biomedicine and Prevention, University of Rome Tor Vergata, 00133 Rome, ItalyHealthcare workers (HCWs) are frequently exposed to a variety of chemical agents, which can result in the development of allergic or irritant contact dermatitis. The present study aimed to assess the prevalence of skin sensitization among HCWs who presented with symptoms of contact dermatitis, considering both occupational and non-occupational risk factors. The study population comprised 127 HCWs who attended routine occupational health surveillance at the Tor Vergata Teaching Hospital in Rome between November 2023 and May 2024. A structured dermatitis questionnaire and patch testing were administered to the participants. Demographic and lifestyle data, including information on occupation, night shift work, smoking habits, and body mass index (BMI), were collected. Patch test positivity was observed in 31.5% of participants, with the most common clinical presentation being erythematous-desquamative allergic contact dermatitis. A significantly higher likelihood of patch test positivity was observed among nurses (57.1%), particularly for nickel sensitization, compared to other occupational groups. A trend towards an association between night shift work and skin sensitization was observed, although this did not reach statistical significance. No significant associations were found for ages over 35 years, sex, or BMI. These findings highlight the elevated risk of contact sensitization among nurses, emphasizing the need for targeted interventions, including exposure reduction strategies and protective measures, to mitigate occupational skin hazards in healthcare settings.https://www.mdpi.com/2079-9721/13/3/77healthcare workerspatch testskin sensitizationcontact dermatitis
spellingShingle Cristiana Ferrari
Giuseppina Somma
Viola Giovinazzo
Margherita Iarossi
Michele Treglia
Margherita Pallocci
Luca Di Giampaolo
Andrea Magrini
Luca Coppeta
The Influence of Occupational Factors on Contact Dermatitis in Symptomatic Healthcare Workers: A Patch Test Study
Diseases
healthcare workers
patch test
skin sensitization
contact dermatitis
title The Influence of Occupational Factors on Contact Dermatitis in Symptomatic Healthcare Workers: A Patch Test Study
title_full The Influence of Occupational Factors on Contact Dermatitis in Symptomatic Healthcare Workers: A Patch Test Study
title_fullStr The Influence of Occupational Factors on Contact Dermatitis in Symptomatic Healthcare Workers: A Patch Test Study
title_full_unstemmed The Influence of Occupational Factors on Contact Dermatitis in Symptomatic Healthcare Workers: A Patch Test Study
title_short The Influence of Occupational Factors on Contact Dermatitis in Symptomatic Healthcare Workers: A Patch Test Study
title_sort influence of occupational factors on contact dermatitis in symptomatic healthcare workers a patch test study
topic healthcare workers
patch test
skin sensitization
contact dermatitis
url https://www.mdpi.com/2079-9721/13/3/77
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