Photochemical and Photobiological Activity of Zn, Cu, Ni, Co, Fe and Mn Unsubstituted Phthalocyanines
Phthalocyanines are a group of porphyrin synthetic molecules. These compounds show outstanding photodynamic properties. This is due to their high ability to photogenerate free radicals, such as <sup>1</sup>O<sub>2</sub> and O<sup>.−</sup><sub>2</sub>....
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2023-11-01
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| author | Franklin Vargas Miguel León Álvaro Álvarez Sergio Dasilva Alexis Maldonado |
| author_facet | Franklin Vargas Miguel León Álvaro Álvarez Sergio Dasilva Alexis Maldonado |
| author_sort | Franklin Vargas |
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| description | Phthalocyanines are a group of porphyrin synthetic molecules. These compounds show outstanding photodynamic properties. This is due to their high ability to photogenerate free radicals, such as <sup>1</sup>O<sub>2</sub> and O<sup>.−</sup><sub>2</sub>. However, the presence of different metals in the central core of phthalocyanines are able to modulate these characteristics. This study demonstrated that the photochemical activity of Zn, Cu, Ni, Co, Fe and Mn unsubstituted phthalocyanines differs, depending on the size and electronic configuration of the central metal. In addition, phthalocyanines showed different levels of photodamage against plasmid pBR322. Outcoming computational calculations will aim to clarify the photodynamic mechanisms of phthalocyanines. |
| format | Article |
| id | doaj-art-b1841d7b98c4447aada4a8b4d50f0660 |
| institution | DOAJ |
| issn | 2673-4583 |
| language | English |
| publishDate | 2023-11-01 |
| publisher | MDPI AG |
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| series | Chemistry Proceedings |
| spelling | doaj-art-b1841d7b98c4447aada4a8b4d50f06602025-08-20T02:53:23ZengMDPI AGChemistry Proceedings2673-45832023-11-011412710.3390/ecsoc-27-16171Photochemical and Photobiological Activity of Zn, Cu, Ni, Co, Fe and Mn Unsubstituted PhthalocyaninesFranklin Vargas0Miguel León1Álvaro Álvarez2Sergio Dasilva3Alexis Maldonado4Laboratorio de Fotoquímica, Instituto Venezolano de Investigaciones Científicas, Caracas 1020-A, VenezuelaLaboratorio de Fotoquímica, Instituto Venezolano de Investigaciones Científicas, Caracas 1020-A, VenezuelaLaboratorio de Fisicoquímica Orgánica, Instituto Venezolano de Investigaciones Científicas, Caracas 1020-A, VenezuelaLaboratorio de Fisicoquímica Orgánica, Instituto Venezolano de Investigaciones Científicas, Caracas 1020-A, VenezuelaLaboratorio de Fisicoquímica Orgánica, Instituto Venezolano de Investigaciones Científicas, Caracas 1020-A, VenezuelaPhthalocyanines are a group of porphyrin synthetic molecules. These compounds show outstanding photodynamic properties. This is due to their high ability to photogenerate free radicals, such as <sup>1</sup>O<sub>2</sub> and O<sup>.−</sup><sub>2</sub>. However, the presence of different metals in the central core of phthalocyanines are able to modulate these characteristics. This study demonstrated that the photochemical activity of Zn, Cu, Ni, Co, Fe and Mn unsubstituted phthalocyanines differs, depending on the size and electronic configuration of the central metal. In addition, phthalocyanines showed different levels of photodamage against plasmid pBR322. Outcoming computational calculations will aim to clarify the photodynamic mechanisms of phthalocyanines.https://www.mdpi.com/2673-4583/14/1/27photochemistryphotobiologysinglet oxygenfluorescencefree radicals |
| spellingShingle | Franklin Vargas Miguel León Álvaro Álvarez Sergio Dasilva Alexis Maldonado Photochemical and Photobiological Activity of Zn, Cu, Ni, Co, Fe and Mn Unsubstituted Phthalocyanines Chemistry Proceedings photochemistry photobiology singlet oxygen fluorescence free radicals |
| title | Photochemical and Photobiological Activity of Zn, Cu, Ni, Co, Fe and Mn Unsubstituted Phthalocyanines |
| title_full | Photochemical and Photobiological Activity of Zn, Cu, Ni, Co, Fe and Mn Unsubstituted Phthalocyanines |
| title_fullStr | Photochemical and Photobiological Activity of Zn, Cu, Ni, Co, Fe and Mn Unsubstituted Phthalocyanines |
| title_full_unstemmed | Photochemical and Photobiological Activity of Zn, Cu, Ni, Co, Fe and Mn Unsubstituted Phthalocyanines |
| title_short | Photochemical and Photobiological Activity of Zn, Cu, Ni, Co, Fe and Mn Unsubstituted Phthalocyanines |
| title_sort | photochemical and photobiological activity of zn cu ni co fe and mn unsubstituted phthalocyanines |
| topic | photochemistry photobiology singlet oxygen fluorescence free radicals |
| url | https://www.mdpi.com/2673-4583/14/1/27 |
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