Activation of the Wnt signaling pathway and its role in epithelial-mesenchymal transition and hepatic fibrosis in alveolar echinococcosis

Activation of the Wnt signaling pathway and its role in epithelial-mesenchymal transition and hepatic fibrosis in alveolar echinococcosis

ObjectiveThis study examined the effects of Echinococcus multilocularis infection on the activation of the Wnt signaling pathway in hepatocytes, its association with epithelial-mesenchymal transition (EMT), and its role in E. multilocularis-induced hepatic fibrosis.MethodsHepatic lesion tissues were...

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Bibliographic Details
Main Authors: Binjie Wu, Yuxuan Yang, Shilei Cheng, Zhixin Wang, Haining Fan
Format: Article
Language:English
Published: Frontiers Media S.A. 2025-05-01
Series:Frontiers in Cellular and Infection Microbiology
Subjects:
DKK-1
epithelial-mesenchymal transition
hepatic alveolar echinococcosis
hepatic fibrosis
Wnt signaling pathway
Online Access:https://www.frontiersin.org/articles/10.3389/fcimb.2025.1583802/full
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