N-terminal truncation of STAT1 transcription factor causes CD3- and CD20-negative non-Hodgkin lymphoma through upregulation of STAT3-mediated oncogenic functions

N-terminal truncation of STAT1 transcription factor causes CD3- and CD20-negative non-Hodgkin lymphoma through upregulation of STAT3-mediated oncogenic functions

Abstract The cytokine-driven transcription factor STAT1 (signal transducer and activator of transcription 1) executes anti-microbial and pro-apoptotic functions, and loss-of-function mutations are associated with increased susceptibility to various infections and the development of tumors. A targete...

Full description

Saved in:
Bibliographic Details
Main Authors: Sana Mumtaz Sheikh, Julia Staab, Martina Bleyer, Aleksandar Ivetic, Fred Lühder, Oliver Wirths, Thomas Meyer
Format: Article
Language:English
Published: BMC 2025-04-01
Series:Cell Communication and Signaling
Online Access:https://doi.org/10.1186/s12964-025-02183-2
Tags: Add Tag
No Tags, Be the first to tag this record!

Similar Items

Similar Items