Design and construction of a fast synthetic modified vaccinia virus Ankara reverse genetics system for advancing vaccine development
The modified vaccinia virus Ankara (MVA) is approved for use as a smallpox and monkeypox virus vaccine and was also designed as a popular recombinant viral vector for vaccine development and gene therapy. However, the extensive genomes of poxviruses present a significant challenge for the developmen...
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| Main Authors: | Zhiqiang Gao, Busen Wang, Tianyu Liu, Zhenghao Zhao, Jinghan Xu, Xiaofan Zhao, Zhe Zhang, Zuyuan Jia, Yilong Yang, Shipo Wu, Wei Chen, Lihua Hou |
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| Format: | Article |
| Language: | English |
| Published: |
Frontiers Media S.A.
2025-04-01
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| Series: | Frontiers in Microbiology |
| Subjects: | |
| Online Access: | https://www.frontiersin.org/articles/10.3389/fmicb.2025.1572706/full |
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