Identification of Long Non-Coding RNA as Potential Biomarkers for the Diagnosis of Postmenopausal Osteoporosis

Conclusion: The lncRNA ZNF529 is significantly overexpressed in PBMC in PMOP, and bioinformatics analysis and validation experiments indicate that it is closely associated with PMOP; thus, it is expected to be a potential diagnostic marker for PMOP.

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Main Authors: Zhu Yihua, Peng Chenjian, Wang Lining, Jiang Shujun, Yang Haomiao, Zhang Kaixuan, Dai Fenglei, Ma Yong, Chu Xudong, Zhang Chunlei, Sun Haitao
Format: Article
Language:English
Published: Wiley 2024-01-01
Series:International Journal of Endocrinology
Online Access:http://dx.doi.org/10.1155/2024/8820697
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author Zhu Yihua
Peng Chenjian
Wang Lining
Jiang Shujun
Yang Haomiao
Zhang Kaixuan
Dai Fenglei
Ma Yong
Chu Xudong
Zhang Chunlei
Sun Haitao
author_facet Zhu Yihua
Peng Chenjian
Wang Lining
Jiang Shujun
Yang Haomiao
Zhang Kaixuan
Dai Fenglei
Ma Yong
Chu Xudong
Zhang Chunlei
Sun Haitao
author_sort Zhu Yihua
collection DOAJ
description Conclusion: The lncRNA ZNF529 is significantly overexpressed in PBMC in PMOP, and bioinformatics analysis and validation experiments indicate that it is closely associated with PMOP; thus, it is expected to be a potential diagnostic marker for PMOP.
format Article
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institution DOAJ
issn 1687-8345
language English
publishDate 2024-01-01
publisher Wiley
record_format Article
series International Journal of Endocrinology
spelling doaj-art-b15212f7b9464ff7ad1912739566ac4e2025-08-20T02:51:43ZengWileyInternational Journal of Endocrinology1687-83452024-01-01202410.1155/2024/8820697Identification of Long Non-Coding RNA as Potential Biomarkers for the Diagnosis of Postmenopausal OsteoporosisZhu Yihua0Peng Chenjian1Wang Lining2Jiang Shujun3Yang Haomiao4Zhang Kaixuan5Dai Fenglei6Ma Yong7Chu Xudong8Zhang Chunlei9Sun Haitao10Laboratory of New Techniques of Restoration & Reconstruction, Institute of Traumatology & OrthopedicsDepartment of Orthopedic SurgeryLaboratory of New Techniques of Restoration & Reconstruction, Institute of Traumatology & OrthopedicsDepartment of Infectious DiseasesDepartment of Orthopedic SurgeryDepartment of Orthopedic SurgeryDepartment of Orthopedic SurgeryLaboratory of New Techniques of Restoration & Reconstruction, Institute of Traumatology & OrthopedicsDepartment of Orthopedic Surgery, Affiliated Huishan Hospital of Xinglin College, Nantong UniversityDepartment of Orthopedic SurgeryDepartment of Orthopedic Surgery, Affiliated Huishan Hospital of Xinglin College, Nantong UniversityConclusion: The lncRNA ZNF529 is significantly overexpressed in PBMC in PMOP, and bioinformatics analysis and validation experiments indicate that it is closely associated with PMOP; thus, it is expected to be a potential diagnostic marker for PMOP.http://dx.doi.org/10.1155/2024/8820697
spellingShingle Zhu Yihua
Peng Chenjian
Wang Lining
Jiang Shujun
Yang Haomiao
Zhang Kaixuan
Dai Fenglei
Ma Yong
Chu Xudong
Zhang Chunlei
Sun Haitao
Identification of Long Non-Coding RNA as Potential Biomarkers for the Diagnosis of Postmenopausal Osteoporosis
International Journal of Endocrinology
title Identification of Long Non-Coding RNA as Potential Biomarkers for the Diagnosis of Postmenopausal Osteoporosis
title_full Identification of Long Non-Coding RNA as Potential Biomarkers for the Diagnosis of Postmenopausal Osteoporosis
title_fullStr Identification of Long Non-Coding RNA as Potential Biomarkers for the Diagnosis of Postmenopausal Osteoporosis
title_full_unstemmed Identification of Long Non-Coding RNA as Potential Biomarkers for the Diagnosis of Postmenopausal Osteoporosis
title_short Identification of Long Non-Coding RNA as Potential Biomarkers for the Diagnosis of Postmenopausal Osteoporosis
title_sort identification of long non coding rna as potential biomarkers for the diagnosis of postmenopausal osteoporosis
url http://dx.doi.org/10.1155/2024/8820697
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