The research progress of thrombospondin type-1 domain 7A and its antibodies in idiopathic membranous nephropathy
Idiopathicmembranous nephropathy(IMN) is an autoimmune glomerular disease with unknown etiology. Current studies have shown that phospholipase A2 receptor(PLA2R) and thrombospondin type-1 domain 7 A(THSD7A) are closely related to the pathogenesis of IMN. At present, serum anti-PLA2R antibody detecti...
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Editorial Department of Journal of Clinical Nephrology
2019-01-01
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| Series: | Linchuang shenzangbing zazhi |
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| Online Access: | http://www.lcszb.com/thesisDetails?columnId=57911796&Fpath=home&index=0 |
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| author | LI Jun WANG Yan-yan CHENG Hong |
| author_facet | LI Jun WANG Yan-yan CHENG Hong |
| author_sort | LI Jun |
| collection | DOAJ |
| description | Idiopathicmembranous nephropathy(IMN) is an autoimmune glomerular disease with unknown etiology. Current studies have shown that phospholipase A2 receptor(PLA2R) and thrombospondin type-1 domain 7 A(THSD7A) are closely related to the pathogenesis of IMN. At present, serum anti-PLA2R antibody detection and glomerular PLA2R antigen staining have been used for clinical diagnosis and prognosis, but the related detection of THSD7A has not been widely used in clinical practice. Therefore, this paper will review the current role and research progress of THSD7A in IMN. |
| format | Article |
| id | doaj-art-b149d38f49ba45f299d8e24e67751877 |
| institution | OA Journals |
| issn | 1671-2390 |
| language | zho |
| publishDate | 2019-01-01 |
| publisher | Editorial Department of Journal of Clinical Nephrology |
| record_format | Article |
| series | Linchuang shenzangbing zazhi |
| spelling | doaj-art-b149d38f49ba45f299d8e24e677518772025-08-20T02:28:49ZzhoEditorial Department of Journal of Clinical NephrologyLinchuang shenzangbing zazhi1671-23902019-01-011962462757911796The research progress of thrombospondin type-1 domain 7A and its antibodies in idiopathic membranous nephropathyLI JunWANG Yan-yanCHENG HongIdiopathicmembranous nephropathy(IMN) is an autoimmune glomerular disease with unknown etiology. Current studies have shown that phospholipase A2 receptor(PLA2R) and thrombospondin type-1 domain 7 A(THSD7A) are closely related to the pathogenesis of IMN. At present, serum anti-PLA2R antibody detection and glomerular PLA2R antigen staining have been used for clinical diagnosis and prognosis, but the related detection of THSD7A has not been widely used in clinical practice. Therefore, this paper will review the current role and research progress of THSD7A in IMN.http://www.lcszb.com/thesisDetails?columnId=57911796&Fpath=home&index=0Idiopathic membranous nephropathyThrombospondin type-1 domain 7A |
| spellingShingle | LI Jun WANG Yan-yan CHENG Hong The research progress of thrombospondin type-1 domain 7A and its antibodies in idiopathic membranous nephropathy Linchuang shenzangbing zazhi Idiopathic membranous nephropathy Thrombospondin type-1 domain 7A |
| title | The research progress of thrombospondin type-1 domain 7A and its antibodies in idiopathic membranous nephropathy |
| title_full | The research progress of thrombospondin type-1 domain 7A and its antibodies in idiopathic membranous nephropathy |
| title_fullStr | The research progress of thrombospondin type-1 domain 7A and its antibodies in idiopathic membranous nephropathy |
| title_full_unstemmed | The research progress of thrombospondin type-1 domain 7A and its antibodies in idiopathic membranous nephropathy |
| title_short | The research progress of thrombospondin type-1 domain 7A and its antibodies in idiopathic membranous nephropathy |
| title_sort | research progress of thrombospondin type 1 domain 7a and its antibodies in idiopathic membranous nephropathy |
| topic | Idiopathic membranous nephropathy Thrombospondin type-1 domain 7A |
| url | http://www.lcszb.com/thesisDetails?columnId=57911796&Fpath=home&index=0 |
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