Depression and Anxiety Among Patients with Epilepsy: A Cross-Sectional Study in Saudi Arabia
<b>Background:</b> Epilepsy is a major neuropsychiatric disorder affecting many people worldwide, with depression and anxiety being common comorbidities that impact the quality of life (QoL). This study aims to examine depression and anxiety in epileptic patients at a tertiary care hospi...
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MDPI AG
2025-05-01
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| author | Mohammed A. Aljaffer Ahmad H. Almadani Ayedh H. Alghamdi Anas A. Alalwan Fay H. Albuqami Khalid O. Altowaijri Lujain A. Alkhalaf Faisal A. Alazmi Shahad F. Aljeri Hadel H. Alhaluli Bandar N. Aljafen |
| author_facet | Mohammed A. Aljaffer Ahmad H. Almadani Ayedh H. Alghamdi Anas A. Alalwan Fay H. Albuqami Khalid O. Altowaijri Lujain A. Alkhalaf Faisal A. Alazmi Shahad F. Aljeri Hadel H. Alhaluli Bandar N. Aljafen |
| author_sort | Mohammed A. Aljaffer |
| collection | DOAJ |
| description | <b>Background:</b> Epilepsy is a major neuropsychiatric disorder affecting many people worldwide, with depression and anxiety being common comorbidities that impact the quality of life (QoL). This study aims to examine depression and anxiety in epileptic patients at a tertiary care hospital, King Khalid University Hospital (KKUH), Riyadh, Saudi Arabia. It also aims to assess participants’ QoL and explore associated risk factors. <b>Methods:</b> This cross-sectional study enrolled 400 participants using a convenience sampling technique. The study tool consisted of a questionnaire, the Arabic version of the Hospital Anxiety and Depression Scale, and the Arabic version of the Quality of Life in Epilepsy Inventory. <b>Results:</b> The results revealed that 48.25% of the participants exhibited depression, and 39.75% exhibited anxiety. There was a statistically significant association between depression and educational level, employment status, history of psychiatric disorders, epilepsy duration, and all subscales of the Quality of Life in Epilepsy Inventory (QOLIE-31). There was also a statistically significant association between anxiety and educational level, employment status, history of psychiatric disorders, epilepsy duration, and all subscales of QOLIE-31. The mean overall QOLIE-31 score was 60.21 ± 20.19, with educational level and employment status, among other factors, being significantly associated with QOLIE-31. <b>Conclusions:</b> Depression and anxiety are prevalent among epileptic patients, requiring routine screening. Supporting education and employment among epileptic patients also appears to be crucial. Strategies to improve QoL among this population should be developed. |
| format | Article |
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| institution | OA Journals |
| issn | 2076-3425 |
| language | English |
| publishDate | 2025-05-01 |
| publisher | MDPI AG |
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| series | Brain Sciences |
| spelling | doaj-art-b1489c9633e34d06822b5d348f28136d2025-08-20T02:33:38ZengMDPI AGBrain Sciences2076-34252025-05-0115548410.3390/brainsci15050484Depression and Anxiety Among Patients with Epilepsy: A Cross-Sectional Study in Saudi ArabiaMohammed A. Aljaffer0Ahmad H. Almadani1Ayedh H. Alghamdi2Anas A. Alalwan3Fay H. Albuqami4Khalid O. Altowaijri5Lujain A. Alkhalaf6Faisal A. Alazmi7Shahad F. Aljeri8Hadel H. Alhaluli9Bandar N. Aljafen10Department of Psychiatry, College of Medicine, King Saud University, Riyadh 11451, Saudi ArabiaDepartment of Psychiatry, College of Medicine, King Saud University, Riyadh 11451, Saudi ArabiaDepartment of Psychiatry, College of Medicine, King Saud University, Riyadh 11451, Saudi ArabiaDepartment of Psychiatry, King Saud University Medical City, King Saud University, Riyadh 11362, Saudi ArabiaDepartment of Psychiatry, King Saud University Medical City, King Saud University, Riyadh 11362, Saudi ArabiaCollege of Medicine, King Saud University, Riyadh 11451, Saudi ArabiaCollege of Medicine, King Saud University, Riyadh 11451, Saudi ArabiaCollege of Medicine, King Saud University, Riyadh 11451, Saudi ArabiaCollege of Medicine, King Saud University, Riyadh 11451, Saudi ArabiaCollege of Medicine, King Saud University, Riyadh 11451, Saudi ArabiaNeurology Unit, Department of Medicine, College of Medicine, King Saud University, Riyadh 11451, Saudi Arabia<b>Background:</b> Epilepsy is a major neuropsychiatric disorder affecting many people worldwide, with depression and anxiety being common comorbidities that impact the quality of life (QoL). This study aims to examine depression and anxiety in epileptic patients at a tertiary care hospital, King Khalid University Hospital (KKUH), Riyadh, Saudi Arabia. It also aims to assess participants’ QoL and explore associated risk factors. <b>Methods:</b> This cross-sectional study enrolled 400 participants using a convenience sampling technique. The study tool consisted of a questionnaire, the Arabic version of the Hospital Anxiety and Depression Scale, and the Arabic version of the Quality of Life in Epilepsy Inventory. <b>Results:</b> The results revealed that 48.25% of the participants exhibited depression, and 39.75% exhibited anxiety. There was a statistically significant association between depression and educational level, employment status, history of psychiatric disorders, epilepsy duration, and all subscales of the Quality of Life in Epilepsy Inventory (QOLIE-31). There was also a statistically significant association between anxiety and educational level, employment status, history of psychiatric disorders, epilepsy duration, and all subscales of QOLIE-31. The mean overall QOLIE-31 score was 60.21 ± 20.19, with educational level and employment status, among other factors, being significantly associated with QOLIE-31. <b>Conclusions:</b> Depression and anxiety are prevalent among epileptic patients, requiring routine screening. Supporting education and employment among epileptic patients also appears to be crucial. Strategies to improve QoL among this population should be developed.https://www.mdpi.com/2076-3425/15/5/484anxietydepressionepilepsyquality of lifeSaudi Arabia |
| spellingShingle | Mohammed A. Aljaffer Ahmad H. Almadani Ayedh H. Alghamdi Anas A. Alalwan Fay H. Albuqami Khalid O. Altowaijri Lujain A. Alkhalaf Faisal A. Alazmi Shahad F. Aljeri Hadel H. Alhaluli Bandar N. Aljafen Depression and Anxiety Among Patients with Epilepsy: A Cross-Sectional Study in Saudi Arabia Brain Sciences anxiety depression epilepsy quality of life Saudi Arabia |
| title | Depression and Anxiety Among Patients with Epilepsy: A Cross-Sectional Study in Saudi Arabia |
| title_full | Depression and Anxiety Among Patients with Epilepsy: A Cross-Sectional Study in Saudi Arabia |
| title_fullStr | Depression and Anxiety Among Patients with Epilepsy: A Cross-Sectional Study in Saudi Arabia |
| title_full_unstemmed | Depression and Anxiety Among Patients with Epilepsy: A Cross-Sectional Study in Saudi Arabia |
| title_short | Depression and Anxiety Among Patients with Epilepsy: A Cross-Sectional Study in Saudi Arabia |
| title_sort | depression and anxiety among patients with epilepsy a cross sectional study in saudi arabia |
| topic | anxiety depression epilepsy quality of life Saudi Arabia |
| url | https://www.mdpi.com/2076-3425/15/5/484 |
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