Clozapine-induced rabbit syndrome: a case report

Rabbit syndrome (RS) is an antipsychoticinduced rhythmic motion of the mouth/lips resembling the chewing movements of a rabbit. The movement consists of a vertical-only motion, at about 5 Hz, with no involvement of the tongue. Long-term exposure to typical antipsychotics has clearly been associated...

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Main Author: Cicek Hocaoglu
Format: Article
Language:English
Published: Wiley 2009-10-01
Series:Mental Illness
Subjects:
Online Access:http://www.pagepress.org/journals/index.php/mi/article/view/870
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author Cicek Hocaoglu
author_facet Cicek Hocaoglu
author_sort Cicek Hocaoglu
collection DOAJ
description Rabbit syndrome (RS) is an antipsychoticinduced rhythmic motion of the mouth/lips resembling the chewing movements of a rabbit. The movement consists of a vertical-only motion, at about 5 Hz, with no involvement of the tongue. Long-term exposure to typical antipsychotics has clearly been associated with RS, but little is known of the risk of RS due to exposure to newer atypical antipsychotics. There have been isolated reports of RS in patients treated with the atypical agents risperidone, aripiprazole, olanzapine, and clozapine. We present the case history of a 44-year old female patient treated for paranoid schizophrenia for 22 years and RS during her last 10-month clozapine treatment. Background information from the literature is also discussed.
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series Mental Illness
spelling doaj-art-b1402f1fde444a218357e9eb4430b76f2025-08-20T03:20:47ZengWileyMental Illness2036-74572036-74652009-10-0111e1e110.4081/mi.2009.e1Clozapine-induced rabbit syndrome: a case reportCicek HocaogluRabbit syndrome (RS) is an antipsychoticinduced rhythmic motion of the mouth/lips resembling the chewing movements of a rabbit. The movement consists of a vertical-only motion, at about 5 Hz, with no involvement of the tongue. Long-term exposure to typical antipsychotics has clearly been associated with RS, but little is known of the risk of RS due to exposure to newer atypical antipsychotics. There have been isolated reports of RS in patients treated with the atypical agents risperidone, aripiprazole, olanzapine, and clozapine. We present the case history of a 44-year old female patient treated for paranoid schizophrenia for 22 years and RS during her last 10-month clozapine treatment. Background information from the literature is also discussed.http://www.pagepress.org/journals/index.php/mi/article/view/870Schizophrenia, Clozapine, Rabbit syndrome
spellingShingle Cicek Hocaoglu
Clozapine-induced rabbit syndrome: a case report
Mental Illness
Schizophrenia, Clozapine, Rabbit syndrome
title Clozapine-induced rabbit syndrome: a case report
title_full Clozapine-induced rabbit syndrome: a case report
title_fullStr Clozapine-induced rabbit syndrome: a case report
title_full_unstemmed Clozapine-induced rabbit syndrome: a case report
title_short Clozapine-induced rabbit syndrome: a case report
title_sort clozapine induced rabbit syndrome a case report
topic Schizophrenia, Clozapine, Rabbit syndrome
url http://www.pagepress.org/journals/index.php/mi/article/view/870
work_keys_str_mv AT cicekhocaoglu clozapineinducedrabbitsyndromeacasereport