Synthesis of Magnolignan, a New Pigment Lightening Component, via a Suzuki-Miyaura Reaction

Magnolignan, 2,2′-dihydroxy-5,5′-dipropyl-biphenyl (1), is a down-regulator of melanin synthesis that inhibits the maturation of tyrosinase. In this study, a concise total synthesis of 1 was achieved in five steps with 50% overall yield starting from commercially available trans-anethole (2) via a S...

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Bibliographic Details
Main Authors: Shuhei Narita, Tetsuhiro Ogura, Toyonobu Usuki
Format: Article
Language:English
Published: Wiley 2013-01-01
Series:Journal of Chemistry
Online Access:http://dx.doi.org/10.1155/2013/686242
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