Synthesis of Magnolignan, a New Pigment Lightening Component, via a Suzuki-Miyaura Reaction
Magnolignan, 2,2′-dihydroxy-5,5′-dipropyl-biphenyl (1), is a down-regulator of melanin synthesis that inhibits the maturation of tyrosinase. In this study, a concise total synthesis of 1 was achieved in five steps with 50% overall yield starting from commercially available trans-anethole (2) via a S...
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| Main Authors: | , , |
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| Format: | Article |
| Language: | English |
| Published: |
Wiley
2013-01-01
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| Series: | Journal of Chemistry |
| Online Access: | http://dx.doi.org/10.1155/2013/686242 |
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| Summary: | Magnolignan, 2,2′-dihydroxy-5,5′-dipropyl-biphenyl (1), is a down-regulator of melanin synthesis that inhibits the maturation of tyrosinase. In this study, a concise total synthesis of 1 was achieved in five steps with 50% overall yield starting from commercially available trans-anethole (2) via a Suzuki-Miyaura reaction. |
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| ISSN: | 2090-9063 2090-9071 |