UHPLC‐Q‐TOF‐MS/MS Dereplication to Identify Chemical Constituents of Hedera helix Leaves in Vietnam
Hedera helix has been reported to contain a wide range of metabolites and produce many pharmacological effects. This research demonstrates the determination and evaluation of the phytochemical profiling of H. helix grown in central Vietnam. Methanolic extract of ivy had been analyzed by ultra-high-p...
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| Main Authors: | , , , , , , , |
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| Format: | Article |
| Language: | English |
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Wiley
2022-01-01
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| Series: | Journal of Analytical Methods in Chemistry |
| Online Access: | http://dx.doi.org/10.1155/2022/1167265 |
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| author | Hong Ngoc Pham Chieu An Tran Thi Diep Trinh Ngoc Lan Nguyen Thi Huynh Nhu Tran Phan Van Nhan Le Ngoc Hung Le Van Trung Phung |
| author_facet | Hong Ngoc Pham Chieu An Tran Thi Diep Trinh Ngoc Lan Nguyen Thi Huynh Nhu Tran Phan Van Nhan Le Ngoc Hung Le Van Trung Phung |
| author_sort | Hong Ngoc Pham |
| collection | DOAJ |
| description | Hedera helix has been reported to contain a wide range of metabolites and produce many pharmacological effects. This research demonstrates the determination and evaluation of the phytochemical profiling of H. helix grown in central Vietnam. Methanolic extract of ivy had been analyzed by ultra-high-performance liquid chromatography-quadrupole time-of-flight mass spectrometry (UHPLC‐Q‐TOF‐MS/MS). MS, and MS/MS experiments were manipulated using both negative and positive ionization modes to provide molecular mass information and production spectra for the structural elucidation of compounds. A total of 46 compounds including 24 triterpene saponins and other compounds were successfully identified of which four established saponin structures have been reported for the first time. This study has provided a base for building a quality control of the raw materials according to the profile of triterpene saponins and assessment of pharmaceutical ingredients of H. helix planted in Vietnam. |
| format | Article |
| id | doaj-art-b12c5a5a509a4be995fb3cba5a9ebf9a |
| institution | Kabale University |
| issn | 2090-8873 |
| language | English |
| publishDate | 2022-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | Journal of Analytical Methods in Chemistry |
| spelling | doaj-art-b12c5a5a509a4be995fb3cba5a9ebf9a2025-02-03T06:05:02ZengWileyJournal of Analytical Methods in Chemistry2090-88732022-01-01202210.1155/2022/1167265UHPLC‐Q‐TOF‐MS/MS Dereplication to Identify Chemical Constituents of Hedera helix Leaves in VietnamHong Ngoc Pham0Chieu An Tran1Thi Diep Trinh2Ngoc Lan Nguyen Thi3Huynh Nhu Tran Phan4Van Nhan Le5Ngoc Hung Le6Van Trung Phung7Center for Research and Technology TransferCenter for Research and Technology TransferDa Lat UniversityNguyen Tat Thanh UniversityCenter for Research and Technology TransferCenter for Research and Technology TransferCenter for Research and Technology TransferCenter for Research and Technology TransferHedera helix has been reported to contain a wide range of metabolites and produce many pharmacological effects. This research demonstrates the determination and evaluation of the phytochemical profiling of H. helix grown in central Vietnam. Methanolic extract of ivy had been analyzed by ultra-high-performance liquid chromatography-quadrupole time-of-flight mass spectrometry (UHPLC‐Q‐TOF‐MS/MS). MS, and MS/MS experiments were manipulated using both negative and positive ionization modes to provide molecular mass information and production spectra for the structural elucidation of compounds. A total of 46 compounds including 24 triterpene saponins and other compounds were successfully identified of which four established saponin structures have been reported for the first time. This study has provided a base for building a quality control of the raw materials according to the profile of triterpene saponins and assessment of pharmaceutical ingredients of H. helix planted in Vietnam.http://dx.doi.org/10.1155/2022/1167265 |
| spellingShingle | Hong Ngoc Pham Chieu An Tran Thi Diep Trinh Ngoc Lan Nguyen Thi Huynh Nhu Tran Phan Van Nhan Le Ngoc Hung Le Van Trung Phung UHPLC‐Q‐TOF‐MS/MS Dereplication to Identify Chemical Constituents of Hedera helix Leaves in Vietnam Journal of Analytical Methods in Chemistry |
| title | UHPLC‐Q‐TOF‐MS/MS Dereplication to Identify Chemical Constituents of Hedera helix Leaves in Vietnam |
| title_full | UHPLC‐Q‐TOF‐MS/MS Dereplication to Identify Chemical Constituents of Hedera helix Leaves in Vietnam |
| title_fullStr | UHPLC‐Q‐TOF‐MS/MS Dereplication to Identify Chemical Constituents of Hedera helix Leaves in Vietnam |
| title_full_unstemmed | UHPLC‐Q‐TOF‐MS/MS Dereplication to Identify Chemical Constituents of Hedera helix Leaves in Vietnam |
| title_short | UHPLC‐Q‐TOF‐MS/MS Dereplication to Identify Chemical Constituents of Hedera helix Leaves in Vietnam |
| title_sort | uhplc q tof ms ms dereplication to identify chemical constituents of hedera helix leaves in vietnam |
| url | http://dx.doi.org/10.1155/2022/1167265 |
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