Role of meningeal lymphatic vessels in brain homeostasis

Role of meningeal lymphatic vessels in brain homeostasis

Meningeal lymphatic vessels (MLVs) form an important bridging structure between the brain and periphery, which drains cerebral metabolites in cerebrospinal fluid (CSF) and brain antigens to deep cervical lymph nodes (dCLNs), to maintain brain homeostasis. Increasing evidence reveals the importance o...

Full description

Saved in:

Bibliographic Details
Main Authors:	Meng-Ying Zhao, Chao-Yuan Ye, Yuan-Cheng Liu, Xiao-Ming Wang, Jun-Cai Fu, Xin-Yuan Liu, Rui Zhu, Yi-Zhao Li, Qing Tian
Format:	Article
Language:	English
Published:	Frontiers Media S.A. 2025-06-01
Series:	Frontiers in Immunology
Subjects:	meningeal lymphatic vessels brain homeostasis cerebrospinal fluid drainage neuroinflammation neurological disorders imaging technique
Online Access:	https://www.frontiersin.org/articles/10.3389/fimmu.2025.1593630/full
Tags:	Add Tag No Tags, Be the first to tag this record!

Similar Items

Brain alterations and neurologic disorder progression induced by lymphatic dysfunction in the head and neck region
by: Hwayeong Cheon, et al.
Published: (2025-04-01)

Modulation of lymphatic vessels in management of liver disease and complications
by: Aarti Sharma, et al.
Published: (2025-04-01)

Microscopic analysis of a primo vessel within a lymphatic vessel in a Sprague-Dawley rat
by: Felix Scholkmann, et al.
Published: (2025-06-01)

Lymphatic circulation and heart failure
by: G. P. Itkin, et al.
Published: (2021-09-01)

Intrathecal synthesis of complement components C3c and C4 in the central nervous system infections with signs of the acute serous meningitis syndrome
by: Tatomirović Željka, et al.
Published: (2002-01-01)

Diagnostic Accuracy of Contrast-enhanced Flair Magnetic Resonance Imaging in Detecting Meningeal Abnormalities in Suspected Cases of Infectious Meningitis
by: Ashapurna Bhagawati, et al.
Published: (2024-12-01)

Frequency of lymphocytic meningitis associated with mumps before and after a mass campaign for mumps vaccination in children from Salvador, Northeast Brazil
by: Nascimento-Carvalho Cristiana M., et al.
Published: (2003-01-01)

Cytokines in cerebrospinal fluid in the case of meningitis in children
by: L. A. Alekseyeva, et al.
Published: (2014-09-01)

Validation of multiplex PCR for the diagnosis of acute bacterial meningitis in culture negative cerebrospinal fluid
by: Sérgio Monteiro de Almeida, et al.
Published: (2019-05-01)

Long-term exercise enhances meningeal lymphatic vessel plasticity and drainage in a mouse model of Alzheimer's disease
by: Yan Chen, et al.
Published: (2025-07-01)

Enhancing Th17 cells drainage through meningeal lymphatic vessels alleviate neuroinflammation after subarachnoid hemorrhage
by: Dandan Gao, et al.
Published: (2024-10-01)

Clinical efficacy of linezolid in the treatment of tuberculous meningitis: a retrospective analysis and literature review
by: Zhen-Tao Fei, et al.
Published: (2025-04-01)

Tuberculous meningitis initially presented with low levels of pleocytosis and protein in the cerebrospinal fluid: a case report
by: Hyung-Kyum Kim, et al.
Published: (2025-07-01)

Сomparative characteristics of serum and cerebrospinal interleukin-6 values in patients with serous and purulent meningitis
by: Ya. S. Ulyanova, et al.
Published: (2025-04-01)

Meningeal Lymphatic and Glymphatic Structures in a Pelagic Delphinid (<i>Delphinus delphis</i>)
by: Olivia N. Jackson, et al.
Published: (2025-03-01)

Occurrence of Pneumococcal Meningitis in Iraq
by: Baghdad Science Journal
Published: (2012-09-01)

Acute bacterial meningitis without cerebrospinal fluid pleocytosis in children: results from a nationwide prospective surveillance system between 2001 and 2022
by: Lama Jaber, et al.
Published: (2024-12-01)

Age-related meningeal extracellular matrix remodeling compromises CNS lymphatic function
by: Kate Hitpass Romero, et al.
Published: (2025-04-01)

Possibilities of immunocytochemical phenotyping of cells in cerebrospinal fluid while children’s bacterial meningitis
by: V. E. Karev, et al.
Published: (2014-09-01)

Normal cerebrospinal fluid protein and associated clinical characteristics in children with tuberculous meningitis
by: Jun-Li Wang, et al.
Published: (2021-01-01)

Analysis of intracranial lesions in patients with HIV-associated cryptococcal meningitis
by: Wei Song, et al.
Published: (2025-02-01)

The nasal lymphatic route of CSF outflow: implications for neurodegenerative disease diagnosis and monitoring
by: Jiwon Chae, et al.
Published: (2024-12-01)

Comparison of cerebrospinal fluid lactate with physical, cytological, and other biochemical characteristics as prognostic factors in acute bacterial meningitis
by: Sérgio Monteiro De Almeida, et al.
Published: (2020-01-01)

Case Report of Neonatal Echoviral Meningitis caused by Echovirus 30 at Aminu Kano Teaching Hospital Kano, Nigeria
by: Surayya Lawan Idris, et al.
Published: (2023-06-01)

Spatiotemporal dynamic changes of meningeal microenvironment influence meningeal lymphatic function following subarachnoid hemorrhage: from inflammatory response to tissue remodeling
by: Bingrui Zhu, et al.
Published: (2025-05-01)

Clinical and epidemiological features of enteroviral meningitis in children during the seasonal increase in incidence in 2023
by: G. P. Martynova, et al.
Published: (2024-06-01)

Microsurgical Lymphatic Vessel Transplantation for Chronic Lymphedema: Long-Term Evaluation of Volume Reduction and Lymphatic Transport Kinetics
by: Wolfram Demmer, et al.
Published: (2025-06-01)

Cerebrospinal fluid type I interferon and cytokine profiles in enteroviral meningitis according to the presence or absence of pleocytosis
by: Kyung Yeon Lee, et al.
Published: (2021-05-01)

Nosocomial meningitis and ventriculitis: clinic, diagnosis, prevention (literature review)
by: M. I. Aybazova, et al.
Published: (2025-06-01)

Traditional and molecular methods for diagnosing bacterial meningitis in Erbil city, Iraq
by: Niga Othman Hamaameen, et al.
Published: (2024-02-01)

Early detection of cerebrospinal fluid/serum glucose ratio: A promising value for mortality prognosis in patients with acute bacterial meningitis
by: Nasrin Khodashenas, et al.
Published: (2025-07-01)

The level of neuron-specific enolase and S-100 protein in the cerebrospinal fluid of patients with acute bacterial meningitis
by: A. V. Sokhan
Published: (2016-08-01)

MUSE and PROPELLER DWI for ADC in parasagittal dura: insights from high-resolution and reduced-distortion DWI
by: Yi-Jui Liu, et al.
Published: (2025-03-01)

Experimental faecal peritonitis alters response to 5-hydroxytryptamine in mesenteric lymphatic vessels
by: A. A. Egorova, et al.
Published: (2020-09-01)

Meta-analysis on effects of lymphatic drainage techniques in the management of carpal tunnel syndrome
by: Sina Shahshenas, et al.
Published: (2025-05-01)

Prevalence and antimicrobial resistance of bacterial meningitis in China from 2017 to 2021: a multicenter retrospective study
by: Chunyan Zhang, et al.
Published: (2024-08-01)

Single‐Cell Metabolic Labeling Probe for Diagnosing Tuberculous Meningitis: A Case Report
by: Jiahao Wang, et al.
Published: (2025-06-01)

Role of urine reagent strips in early diagnosis of meningitis
by: Preeti Singh, et al.
Published: (2025-01-01)

SARS-CoV-2 investigation in cerebrospinal fluid from meningitis patients during the first pandemic wave
by: Maria Cecilia Cergole-Novella, et al.
Published: (2025-09-01)

Photoacoustic detecting of brain lymphatic dysfunction in inflammatory models
by: Meng Wang, et al.
Published: (2025-09-01)