Transcriptomic Dysregulation in Animal Models of Attention‐Deficit Hyperactivity Disorder and Nicotine Dependence Suggests Shared Neural Mechanisms

Transcriptomic Dysregulation in Animal Models of Attention‐Deficit Hyperactivity Disorder and Nicotine Dependence Suggests Shared Neural Mechanisms

ABSTRACT Introduction Attention‐deficit‐hyperactivity disorder (ADHD) is highly heritable and increases the likelihood of nicotine dependence (ND). The self‐medication hypothesis of nicotine use in ADHD proposes that ADHD patients seek nicotine for its ability to improve their symptoms, and they hav...

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Bibliographic Details
Main Authors: Sarah Van Horn, Heather Driscoll, Donna J Toufexis
Format: Article
Language:English
Published: Wiley 2025-03-01
Series:Brain and Behavior
Subjects:
attention‐deficit hyperactivity disorder
differential gene expression
pathway enrichment analysis
drug addiction
MAP kinase
nicotine
Online Access:https://doi.org/10.1002/brb3.70444
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