Serum Concentration at 24 h With Intensive Beta-Lactam Therapy in Sepsis and Septic Shock: A Prospective Study
Conclusion: Nonrenally adjusted doses of beta-lactams administered by extended infusion showed good attainment of effective concentrations and few toxic concentrations in critically ill patients with sepsis or septic shock. Further studies are needed to better define the association between toxic co...
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| Main Authors: | , , , , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Wiley
2024-01-01
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| Series: | Critical Care Research and Practice |
| Online Access: | http://dx.doi.org/10.1155/2024/9757792 |
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| _version_ | 1850160113318363136 |
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| author | Evelyne Thériault Massilia Benali Samuel Starnino Hugues Blain Nicolas Goettel Bianca Beloin-Jubinville Amélie Marsot Francois Lamontagne |
| author_facet | Evelyne Thériault Massilia Benali Samuel Starnino Hugues Blain Nicolas Goettel Bianca Beloin-Jubinville Amélie Marsot Francois Lamontagne |
| author_sort | Evelyne Thériault |
| collection | DOAJ |
| description | Conclusion: Nonrenally adjusted doses of beta-lactams administered by extended infusion showed good attainment of effective concentrations and few toxic concentrations in critically ill patients with sepsis or septic shock. Further studies are needed to better define the association between toxic concentrations and toxicity manifestations. |
| format | Article |
| id | doaj-art-b10ffd5e67f54c86a4b13526abd2f8f8 |
| institution | OA Journals |
| issn | 2090-1313 |
| language | English |
| publishDate | 2024-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | Critical Care Research and Practice |
| spelling | doaj-art-b10ffd5e67f54c86a4b13526abd2f8f82025-08-20T02:23:15ZengWileyCritical Care Research and Practice2090-13132024-01-01202410.1155/2024/9757792Serum Concentration at 24 h With Intensive Beta-Lactam Therapy in Sepsis and Septic Shock: A Prospective StudyEvelyne Thériault0Massilia Benali1Samuel Starnino2Hugues Blain3Nicolas Goettel4Bianca Beloin-Jubinville5Amélie Marsot6Francois Lamontagne7Department of PharmacyDepartment of PharmacyDepartment of PharmacyDepartment of PharmacyDepartment of PharmacyDepartment of PharmacyFaculté de PharmacieDepartment of MedicineConclusion: Nonrenally adjusted doses of beta-lactams administered by extended infusion showed good attainment of effective concentrations and few toxic concentrations in critically ill patients with sepsis or septic shock. Further studies are needed to better define the association between toxic concentrations and toxicity manifestations.http://dx.doi.org/10.1155/2024/9757792 |
| spellingShingle | Evelyne Thériault Massilia Benali Samuel Starnino Hugues Blain Nicolas Goettel Bianca Beloin-Jubinville Amélie Marsot Francois Lamontagne Serum Concentration at 24 h With Intensive Beta-Lactam Therapy in Sepsis and Septic Shock: A Prospective Study Critical Care Research and Practice |
| title | Serum Concentration at 24 h With Intensive Beta-Lactam Therapy in Sepsis and Septic Shock: A Prospective Study |
| title_full | Serum Concentration at 24 h With Intensive Beta-Lactam Therapy in Sepsis and Septic Shock: A Prospective Study |
| title_fullStr | Serum Concentration at 24 h With Intensive Beta-Lactam Therapy in Sepsis and Septic Shock: A Prospective Study |
| title_full_unstemmed | Serum Concentration at 24 h With Intensive Beta-Lactam Therapy in Sepsis and Septic Shock: A Prospective Study |
| title_short | Serum Concentration at 24 h With Intensive Beta-Lactam Therapy in Sepsis and Septic Shock: A Prospective Study |
| title_sort | serum concentration at 24 h with intensive beta lactam therapy in sepsis and septic shock a prospective study |
| url | http://dx.doi.org/10.1155/2024/9757792 |
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