Seroprevalence of Human Brucellosis among Patients admitted with PUO (Pyrexia of Unknown Origin) at a Tertiary Care Hospital in North India

Background Brucellosis is a disease reported in many parts of the world including India and the disease is also one of the important causes of PUO Pyrexia of Unknown Origin. The present study was conducted with an aim to determine the seroprevalence of human Brucellosis in patie...

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Bibliographic Details
Main Authors: Sahil Langeh, Lubna Mir, Dinesh Kumar, Bhavna Sahni, Kiran Bala
Format: Article
Language:English
Published: Rajiv Gandhi University of Health Sciences 2024-01-01
Series:RGUHS Journal of Nursing Sciences
Online Access:https://journalgrid.com/view/article/rjns/12434201
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Summary:Background Brucellosis is a disease reported in many parts of the world including India and the disease is also one of the important causes of PUO Pyrexia of Unknown Origin. The present study was conducted with an aim to determine the seroprevalence of human Brucellosis in patients reporting with PUO.Method A cross-sectional hospital-based study was conducted at a tertiary care medical teaching institute in Northern India. A total of 369 serum samples were collected from PUO cases and tested for human Brucellosis by using Rose Bengal Plate Agglutination Test RBPT Serum Tube Agglutination Test STAT Enzyme linked Immunoassay ELISA.Results Overall seroprevalence in our study was found to be 2.98 0.5 0.8 and 1.6 by RBPT STAT and ELISA respectively.Conclusion In spite of the low prevalence of human Brucellosis clinicians must maintain a high index of suspicion for the possibility of a patient suffering from Brucellosis while encountering a case of PUO and it is advisable to elicit history in terms of certain occupations and risk factors for Brucellosis in patients reporting with PUO.
ISSN:2231-6051
2583-6757