Na+/K+-ATPase: a multifunctional target in type 2 diabetes and pancreatic islets

Na+/K+-ATPase: a multifunctional target in type 2 diabetes and pancreatic islets

Type 2 diabetes (T2D) is a widespread metabolic disorder marked by hyperglycemia, arising from insulin resistance and relative insulin deficiency. This review investigates the critical role of Na+/K+-ATPase (NKA), a transmembrane protein essential for maintaining cellular ion gradients, in the patho...

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Bibliographic Details
Main Authors: Lisha Mou, Zhenkun Fu, Tony Bowei Wang, Yuxian Chen, Ziqi Luo, Xinyu Wang, Zuhui Pu
Format: Article
Language:English
Published: Frontiers Media S.A. 2025-02-01
Series:Frontiers in Immunology
Subjects:
diabetes
type 2 diabetes
sodium-potassium ATPase
islet
β-cells
therapeutic target
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2025.1555310/full
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