Coinfection with Cryptococcus Gattii and Mycobacterium Tuberculosis in an Otherwise Healthy 18-Year-Old Woman

A case of Cryptococcus gattii (pulmonary and central nervous system) and Mycobacterium tuberculosis (pulmonary) coinfection in an otherwise healthy young woman is reported. The patient presented with a two-month history of dry cough. She had an unremarkable medical history. Both tuberculosis and cry...

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Main Authors: Lindsay Van Tongeren, Tawimas Shaipanich, John A Fleetham
Format: Article
Language:English
Published: Wiley 2011-01-01
Series:Canadian Respiratory Journal
Online Access:http://dx.doi.org/10.1155/2011/812345
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author Lindsay Van Tongeren
Tawimas Shaipanich
John A Fleetham
author_facet Lindsay Van Tongeren
Tawimas Shaipanich
John A Fleetham
author_sort Lindsay Van Tongeren
collection DOAJ
description A case of Cryptococcus gattii (pulmonary and central nervous system) and Mycobacterium tuberculosis (pulmonary) coinfection in an otherwise healthy young woman is reported. The patient presented with a two-month history of dry cough. She had an unremarkable medical history. Both tuberculosis and cryptococcosis were diagnosed following bronchoscopy, and a subsequent lumbar puncture revealed C gattii in the cerebrospinal fluid. There is evidence that both M tuberculosis and C gattii may have suppressive effects on the host immune system. This suggests a mechanism by which an otherwise healthy individual developed these two infections.
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spelling doaj-art-b0f6474fa0f54e1cbf46d0b90d9acb962025-08-20T02:23:36ZengWileyCanadian Respiratory Journal1198-22412011-01-01184e62e6310.1155/2011/812345Coinfection with Cryptococcus Gattii and Mycobacterium Tuberculosis in an Otherwise Healthy 18-Year-Old WomanLindsay Van Tongeren0Tawimas Shaipanich1John A Fleetham2Division of Respiratory Medicine, University of British Columbia, Vancouver, British Columbia, CanadaDivision of Respiratory Medicine, University of British Columbia, Vancouver, British Columbia, CanadaDivision of Respiratory Medicine, University of British Columbia, Vancouver, British Columbia, CanadaA case of Cryptococcus gattii (pulmonary and central nervous system) and Mycobacterium tuberculosis (pulmonary) coinfection in an otherwise healthy young woman is reported. The patient presented with a two-month history of dry cough. She had an unremarkable medical history. Both tuberculosis and cryptococcosis were diagnosed following bronchoscopy, and a subsequent lumbar puncture revealed C gattii in the cerebrospinal fluid. There is evidence that both M tuberculosis and C gattii may have suppressive effects on the host immune system. This suggests a mechanism by which an otherwise healthy individual developed these two infections.http://dx.doi.org/10.1155/2011/812345
spellingShingle Lindsay Van Tongeren
Tawimas Shaipanich
John A Fleetham
Coinfection with Cryptococcus Gattii and Mycobacterium Tuberculosis in an Otherwise Healthy 18-Year-Old Woman
Canadian Respiratory Journal
title Coinfection with Cryptococcus Gattii and Mycobacterium Tuberculosis in an Otherwise Healthy 18-Year-Old Woman
title_full Coinfection with Cryptococcus Gattii and Mycobacterium Tuberculosis in an Otherwise Healthy 18-Year-Old Woman
title_fullStr Coinfection with Cryptococcus Gattii and Mycobacterium Tuberculosis in an Otherwise Healthy 18-Year-Old Woman
title_full_unstemmed Coinfection with Cryptococcus Gattii and Mycobacterium Tuberculosis in an Otherwise Healthy 18-Year-Old Woman
title_short Coinfection with Cryptococcus Gattii and Mycobacterium Tuberculosis in an Otherwise Healthy 18-Year-Old Woman
title_sort coinfection with cryptococcus gattii and mycobacterium tuberculosis in an otherwise healthy 18 year old woman
url http://dx.doi.org/10.1155/2011/812345
work_keys_str_mv AT lindsayvantongeren coinfectionwithcryptococcusgattiiandmycobacteriumtuberculosisinanotherwisehealthy18yearoldwoman
AT tawimasshaipanich coinfectionwithcryptococcusgattiiandmycobacteriumtuberculosisinanotherwisehealthy18yearoldwoman
AT johnafleetham coinfectionwithcryptococcusgattiiandmycobacteriumtuberculosisinanotherwisehealthy18yearoldwoman