Clinical Relevance of HLA Antibody Monitoring after Kidney Transplantation
In kidney transplantation, antibody-mediated allograft injury caused by donor HLA-specific antibodies (DSA) has recently been identified as one of the major causes of late graft loss. This paper gives a brief overview on the impact of DSA development on graft outcome in organ transplantation with a...
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| Main Authors: | , , , |
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| Format: | Article |
| Language: | English |
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Wiley
2014-01-01
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| Series: | Journal of Immunology Research |
| Online Access: | http://dx.doi.org/10.1155/2014/845040 |
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| _version_ | 1850160107471503360 |
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| author | Christian Morath Gerhard Opelz Martin Zeier Caner Süsal |
| author_facet | Christian Morath Gerhard Opelz Martin Zeier Caner Süsal |
| author_sort | Christian Morath |
| collection | DOAJ |
| description | In kidney transplantation, antibody-mediated allograft injury caused by donor HLA-specific antibodies (DSA) has recently been identified as one of the major causes of late graft loss. This paper gives a brief overview on the impact of DSA development on graft outcome in organ transplantation with a focus on risk factors for de novo alloantibody induction and recently published guidelines for monitoring of DSA during the posttransplant phase. |
| format | Article |
| id | doaj-art-b0f2796c24f7471d8ecab2c3bf5ad8df |
| institution | OA Journals |
| issn | 2314-8861 2314-7156 |
| language | English |
| publishDate | 2014-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | Journal of Immunology Research |
| spelling | doaj-art-b0f2796c24f7471d8ecab2c3bf5ad8df2025-08-20T02:23:15ZengWileyJournal of Immunology Research2314-88612314-71562014-01-01201410.1155/2014/845040845040Clinical Relevance of HLA Antibody Monitoring after Kidney TransplantationChristian Morath0Gerhard Opelz1Martin Zeier2Caner Süsal3Department of Nephrology, University of Heidelberg, Im Neuenheimer Feld 162, 69120 Heidelberg, GermanyDepartment of Transplantation Immunology, Institute of Immunology, University of Heidelberg, Im Neuenheimer Feld 305, 69120 Heidelberg, GermanyDepartment of Nephrology, University of Heidelberg, Im Neuenheimer Feld 162, 69120 Heidelberg, GermanyDepartment of Transplantation Immunology, Institute of Immunology, University of Heidelberg, Im Neuenheimer Feld 305, 69120 Heidelberg, GermanyIn kidney transplantation, antibody-mediated allograft injury caused by donor HLA-specific antibodies (DSA) has recently been identified as one of the major causes of late graft loss. This paper gives a brief overview on the impact of DSA development on graft outcome in organ transplantation with a focus on risk factors for de novo alloantibody induction and recently published guidelines for monitoring of DSA during the posttransplant phase.http://dx.doi.org/10.1155/2014/845040 |
| spellingShingle | Christian Morath Gerhard Opelz Martin Zeier Caner Süsal Clinical Relevance of HLA Antibody Monitoring after Kidney Transplantation Journal of Immunology Research |
| title | Clinical Relevance of HLA Antibody Monitoring after Kidney Transplantation |
| title_full | Clinical Relevance of HLA Antibody Monitoring after Kidney Transplantation |
| title_fullStr | Clinical Relevance of HLA Antibody Monitoring after Kidney Transplantation |
| title_full_unstemmed | Clinical Relevance of HLA Antibody Monitoring after Kidney Transplantation |
| title_short | Clinical Relevance of HLA Antibody Monitoring after Kidney Transplantation |
| title_sort | clinical relevance of hla antibody monitoring after kidney transplantation |
| url | http://dx.doi.org/10.1155/2014/845040 |
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