The role disorders at system of cytokines in pathogenesis of Helicobacter pilory-associated pathology
Fifty five Khakas people with Helicobacter pylori-associated ulcer disease and chronic gastritis were examined in order to estimate the production of IL-2, IL-4, and IL-10 interleukins in patients with chronic Helicobacter pylori persistence. The subpopulation composition of lymphocytes of periphera...
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| Format: | Article |
| Language: | English |
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Siberian State Medical University (Tomsk)
2011-12-01
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| Series: | Бюллетень сибирской медицины |
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| Online Access: | https://bulletin.ssmu.ru/jour/article/view/1492 |
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| author | Ye. S. Ageyeva O. V. Shtygasheva V. M. Iptyshev N. V. Ryazantseva |
| author_facet | Ye. S. Ageyeva O. V. Shtygasheva V. M. Iptyshev N. V. Ryazantseva |
| author_sort | Ye. S. Ageyeva |
| collection | DOAJ |
| description | Fifty five Khakas people with Helicobacter pylori-associated ulcer disease and chronic gastritis were examined in order to estimate the production of IL-2, IL-4, and IL-10 interleukins in patients with chronic Helicobacter pylori persistence. The subpopulation composition of lymphocytes of peripheral blood was determined by the method of flow-through cytofluorometry. Apoptosis was estimated by the method of optical microscopy. The IL-2, IL-4, IL-10 production in supernatants was determined by the solidphase immunoenzymometric method. Changes revealed in the blood of patients infected with Helicobacter pylori were characterized by the increased amount and subpopulation disbalance of lymphocytes, apoptosis modification, and depletion of lymphocyte functional activity. |
| format | Article |
| id | doaj-art-b0e419205cea4ef8b38499a69989bae4 |
| institution | DOAJ |
| issn | 1682-0363 1819-3684 |
| language | English |
| publishDate | 2011-12-01 |
| publisher | Siberian State Medical University (Tomsk) |
| record_format | Article |
| series | Бюллетень сибирской медицины |
| spelling | doaj-art-b0e419205cea4ef8b38499a69989bae42025-08-20T03:21:44ZengSiberian State Medical University (Tomsk)Бюллетень сибирской медицины1682-03631819-36842011-12-011065810.20538/1682-0363-2011-6-5-8998The role disorders at system of cytokines in pathogenesis of Helicobacter pilory-associated pathologyYe. S. Ageyeva0O. V. Shtygasheva1V. M. Iptyshev2N. V. Ryazantseva3Хакасский государственный университет им. Н.Ф. КатановаХакасский государственный университет им. Н.Ф. КатановаХакасская республиканская больница им. Г.Я. РемишевскойСибирский государственный медицинский университетFifty five Khakas people with Helicobacter pylori-associated ulcer disease and chronic gastritis were examined in order to estimate the production of IL-2, IL-4, and IL-10 interleukins in patients with chronic Helicobacter pylori persistence. The subpopulation composition of lymphocytes of peripheral blood was determined by the method of flow-through cytofluorometry. Apoptosis was estimated by the method of optical microscopy. The IL-2, IL-4, IL-10 production in supernatants was determined by the solidphase immunoenzymometric method. Changes revealed in the blood of patients infected with Helicobacter pylori were characterized by the increased amount and subpopulation disbalance of lymphocytes, apoptosis modification, and depletion of lymphocyte functional activity.https://bulletin.ssmu.ru/jour/article/view/1492helicobacter pyloriulcerative diseasekhakassesapoptosisimmune responselymphocytes |
| spellingShingle | Ye. S. Ageyeva O. V. Shtygasheva V. M. Iptyshev N. V. Ryazantseva The role disorders at system of cytokines in pathogenesis of Helicobacter pilory-associated pathology Бюллетень сибирской медицины helicobacter pylori ulcerative disease khakasses apoptosis immune response lymphocytes |
| title | The role disorders at system of cytokines in pathogenesis of Helicobacter pilory-associated pathology |
| title_full | The role disorders at system of cytokines in pathogenesis of Helicobacter pilory-associated pathology |
| title_fullStr | The role disorders at system of cytokines in pathogenesis of Helicobacter pilory-associated pathology |
| title_full_unstemmed | The role disorders at system of cytokines in pathogenesis of Helicobacter pilory-associated pathology |
| title_short | The role disorders at system of cytokines in pathogenesis of Helicobacter pilory-associated pathology |
| title_sort | role disorders at system of cytokines in pathogenesis of helicobacter pilory associated pathology |
| topic | helicobacter pylori ulcerative disease khakasses apoptosis immune response lymphocytes |
| url | https://bulletin.ssmu.ru/jour/article/view/1492 |
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