Patient-centered intrathecal morphine dose response in major abdominal surgeries when augmented by innovative five-drug antiemetic prophylaxis

Patient-centered intrathecal morphine dose response in major abdominal surgeries when augmented by innovative five-drug antiemetic prophylaxis

BackgroundFor abdominal surgery involving cephalad surgical trespass (such as sleeve gastrectomy and pancreatectomy), existing intrathecal morphine (ITM) recommendations of ≤150 μg may not achieve meaningful analgesia, potentially leading to side effects of intravenous opioids during or after surger...

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Bibliographic Details
Main Authors: Brian A. Williams, Daniel E. Hall, Chelsee Dalessandro, Kelly E. Garbelotti, John M. Ludden
Format: Article
Language:English
Published: Frontiers Media S.A. 2025-02-01
Series:Frontiers in Anesthesiology
Subjects:
palonosetron
perphenazine
aprepitant
diphenhydramine
dexamethasone
intrathecal morphine
Online Access:https://www.frontiersin.org/articles/10.3389/fanes.2025.1521409/full
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