Cefiderocol-Resistant Elizabethkingia anophelis Bacteremia Following WATCHMAN Implantation: A Case Report and Review of the Literature
Elizabethkingia anophelis is an emerging pathogen associated with nosocomial and community outbreaks. Treatment of infection caused by E. anophelis is not well-defined given its extensive drug resistance profile, and infection carries a poor prognosis. E. anophelis is intrinsically resistant to many...
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| Format: | Article |
| Language: | English |
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Wiley
2025-01-01
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| Series: | Case Reports in Infectious Diseases |
| Online Access: | http://dx.doi.org/10.1155/crdi/5221364 |
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| author | Anna DeFrank Michael Bosco Sigridh Muñoz Gómez Amit Dhaliwal |
| author_facet | Anna DeFrank Michael Bosco Sigridh Muñoz Gómez Amit Dhaliwal |
| author_sort | Anna DeFrank |
| collection | DOAJ |
| description | Elizabethkingia anophelis is an emerging pathogen associated with nosocomial and community outbreaks. Treatment of infection caused by E. anophelis is not well-defined given its extensive drug resistance profile, and infection carries a poor prognosis. E. anophelis is intrinsically resistant to many classes of antibiotics including carbapenems and polymyxins due to multiple resistance genes. Resistance to novel β-lactam/β-lactamase inhibitors has also been reported. The activity of cefiderocol (FDC) is unknown. Here, we describe a case of FDC-resistant E. anophelis bacteremia following WATCHMAN implantation. To our knowledge, this is the first reported case of FDC resistance amongst Elizabethkingia spp. |
| format | Article |
| id | doaj-art-b0e33baa70ec4e59a09f7c38d1834ee0 |
| institution | Kabale University |
| issn | 2090-6633 |
| language | English |
| publishDate | 2025-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | Case Reports in Infectious Diseases |
| spelling | doaj-art-b0e33baa70ec4e59a09f7c38d1834ee02025-08-20T03:48:11ZengWileyCase Reports in Infectious Diseases2090-66332025-01-01202510.1155/crdi/5221364Cefiderocol-Resistant Elizabethkingia anophelis Bacteremia Following WATCHMAN Implantation: A Case Report and Review of the LiteratureAnna DeFrank0Michael Bosco1Sigridh Muñoz Gómez2Amit Dhaliwal3Department of PharmacyDepartment of PharmacyDepartment of MedicineDepartment of MedicineElizabethkingia anophelis is an emerging pathogen associated with nosocomial and community outbreaks. Treatment of infection caused by E. anophelis is not well-defined given its extensive drug resistance profile, and infection carries a poor prognosis. E. anophelis is intrinsically resistant to many classes of antibiotics including carbapenems and polymyxins due to multiple resistance genes. Resistance to novel β-lactam/β-lactamase inhibitors has also been reported. The activity of cefiderocol (FDC) is unknown. Here, we describe a case of FDC-resistant E. anophelis bacteremia following WATCHMAN implantation. To our knowledge, this is the first reported case of FDC resistance amongst Elizabethkingia spp.http://dx.doi.org/10.1155/crdi/5221364 |
| spellingShingle | Anna DeFrank Michael Bosco Sigridh Muñoz Gómez Amit Dhaliwal Cefiderocol-Resistant Elizabethkingia anophelis Bacteremia Following WATCHMAN Implantation: A Case Report and Review of the Literature Case Reports in Infectious Diseases |
| title | Cefiderocol-Resistant Elizabethkingia anophelis Bacteremia Following WATCHMAN Implantation: A Case Report and Review of the Literature |
| title_full | Cefiderocol-Resistant Elizabethkingia anophelis Bacteremia Following WATCHMAN Implantation: A Case Report and Review of the Literature |
| title_fullStr | Cefiderocol-Resistant Elizabethkingia anophelis Bacteremia Following WATCHMAN Implantation: A Case Report and Review of the Literature |
| title_full_unstemmed | Cefiderocol-Resistant Elizabethkingia anophelis Bacteremia Following WATCHMAN Implantation: A Case Report and Review of the Literature |
| title_short | Cefiderocol-Resistant Elizabethkingia anophelis Bacteremia Following WATCHMAN Implantation: A Case Report and Review of the Literature |
| title_sort | cefiderocol resistant elizabethkingia anophelis bacteremia following watchman implantation a case report and review of the literature |
| url | http://dx.doi.org/10.1155/crdi/5221364 |
| work_keys_str_mv | AT annadefrank cefiderocolresistantelizabethkingiaanophelisbacteremiafollowingwatchmanimplantationacasereportandreviewoftheliterature AT michaelbosco cefiderocolresistantelizabethkingiaanophelisbacteremiafollowingwatchmanimplantationacasereportandreviewoftheliterature AT sigridhmunozgomez cefiderocolresistantelizabethkingiaanophelisbacteremiafollowingwatchmanimplantationacasereportandreviewoftheliterature AT amitdhaliwal cefiderocolresistantelizabethkingiaanophelisbacteremiafollowingwatchmanimplantationacasereportandreviewoftheliterature |