Improving cognitive impairment through chronic consumption of natural compounds/extracts: a systematic review and meta-analysis of randomized controlled trials

Improving cognitive impairment through chronic consumption of natural compounds/extracts: a systematic review and meta-analysis of randomized controlled trials

IntroductionThis systematic review and meta-analysis aimed to compare the efficacy of extended supplementation (≥6 weeks) with natural compounds or extracts in improving cognitive function in patients with mild cognitive impairment (MCI) or Alzheimer’s disease (AD).MethodsA comprehensive literature...

Full description

Saved in:

Bibliographic Details
Main Authors:	Long Ngo Hoang, Haesung Lee, Sook Jeong Lee
Format:	Article
Language:	English
Published:	Frontiers Media S.A. 2025-01-01
Series:	Frontiers in Aging Neuroscience
Subjects:	aging Alzheimer’s disease cognitive dysfunction meta-analysis neurodegeneration
Online Access:	https://www.frontiersin.org/articles/10.3389/fnagi.2024.1531278/full
Tags:	Add Tag No Tags, Be the first to tag this record!

Similar Items

The synergistic extract of Zophobas atratus and Tenebrio molitor regulates neuroplasticity and oxidative stress in a scopolamine-induced cognitive impairment model
by: Ngoc Buu Tran, et al.
Published: (2025-04-01)

Gut Microbiota and Neurovascular Patterns in Amnestic Mild Cognitive Impairment
by: Alexis B. Kazen, et al.
Published: (2025-05-01)

Differential effects of neurodegeneration biomarkers on subclinical cognitive decline
by: Andrew P. Merluzzi, et al.
Published: (2019-01-01)

Some aspects of treatment for cognitive impairments. Cyticolin: pharmacological characteristics, possible benefits, aspects of use
by: N. V. Trofimova, et al.
Published: (2016-01-01)

Older Amyloid Beta as a Candidate Blood Biomarker of Early Cognitive Decline in the Elderly—A Preliminary Study
by: Oliwia McFarlane, et al.
Published: (2025-03-01)

Editorial: Lifestyle and environmental influences on Alzheimer's disease: exploring the roles of diet, exercise, cognitive reserve, sleep, and air quality
by: Ruogu Cheng, et al.
Published: (2025-07-01)

Validation of the Addenbrooke’s Cognitive Examination III (ACE-III) in Alzheimer’s disease and Mild Cognitive Impairment
by: Majid Mahmoud alilou, et al.
Published: (2019-04-01)

Acupuncture for patients with mild cognitive impairment: a randomized, patient–assessor-blinded, sham-controlled pilot study
by: Yujin Choi, et al.
Published: (2025-07-01)

Constipation and risk of cognitive impairment and dementia in adults: a systematic review and meta-analysis
by: Qiyue Wang, et al.
Published: (2025-06-01)

Meditation for subjective cognitive decline, mild cognitive impairment and Alzheimer’s disease: a systematic review and meta-analysis of randomized controlled trials
by: Jiaxin Shi, et al.
Published: (2025-05-01)

Underestimated virus impaired cognition-more evidence and more work to do
by: Maher Un Nisa Awan, et al.
Published: (2025-05-01)

Neurological soft signs in neurodegenerative dementias: Results of the DemeNSS study
by: Federico Emanuele Pozzi, et al.
Published: (2025-06-01)

Amyloid-beta 40 as a biomarker of cognitive impairment in acute ischemic stroke
by: Aleksey A. Kulesh, et al.
Published: (2017-10-01)

INSULIN RESISTANCE AS A RISK FACTOR FOR COGNITIVE DYSFUNCTION
by: Antoniya Hachmeriyan, et al.
Published: (2025-03-01)

The effect of tanshinones on cognitive impairments in animal models of Alzheimer’s disease: a systematic review and meta-analysis
by: Shuwei Wang, et al.
Published: (2025-02-01)

Vascular and glymphatic dysfunction as drivers of cognitive impairment in Alzheimer's disease: Insights from computational approaches
by: Gehan Fatima, et al.
Published: (2025-05-01)

Efficacy of medications in controlling cognitive dysfunction in Alzheimer’s : a systematic review
by: Sâmia Moreira de Andrade, et al.
Published: (2025-08-01)

Cerebellar MRI-based radiomics models for identifying mild cognitive impairment: a retrospective multicenter study in Southeast China
by: Jianping Lu, et al.
Published: (2025-07-01)

Accuracy of the Brief Cognitive Screening Battery for diagnosing Alzheimer's disease defined by cerebrospinal fluid biomarkers and AT(N) classification: a case-control study
by: Patrícia Regina Henrique Peles, et al.
Published: (2021-11-01)

VEXAS Syndrome and Alzheimer’s Disease—Are There Connections?
by: Aleksandra Sowa, et al.
Published: (2025-05-01)

Prevalence and risk of cognitive impairment among patients with asthma: A systematic review and meta‐analysis
by: Ganesh Bushi, et al.
Published: (2025-03-01)

Revolutionizing early Alzheimer's disease and mild cognitive impairment diagnosis: a deep learning MRI meta-analysis
by: Li-xue Wang, et al.
Published: (2024-08-01)

A prospective study of cognitive impairment in Parkinson’s disease: clinical, neuropsychological, and neuroimaging correlates
by: Ahmed A. Gaballa, et al.
Published: (2025-06-01)

Role of Voice Signal Analysis in Screening for Cognitive Impairment: A Study on Community-dwelling Older Adults
by: Sangdo LEE, et al.
Published: (2025-03-01)

Vascular endotelial dysfunction is a pathogenetic factor in the development of neurodegenerative diseases and cognitive impairment
by: N. V. Goncharov, et al.
Published: (2020-10-01)

Effect of probiotics on cognitive function and cardiovascular risk factors in mild cognitive impairment and Alzheimer’s disease: an umbrella meta-analysis
by: Bin Xiao, et al.
Published: (2025-04-01)

Models and mechanisms of post-stroke dementia and cognitive impairment
by: Romeesa Khan, et al.
Published: (2025-05-01)

Spatial orientation tasks show moderate to high accuracy for the diagnosis of mild cognitive impairment: a systematic literature review
by: Raquel Quimas Molina da Costa, et al.
Published: (2020-12-01)

DDL-920 mediated enhancement of γ-oscillations targeting γ-aminobutyric acid receptors: a novel therapeutic strategy to improve cognition in Alzheimer's disease
by: Ali Aamir, et al.
Published: (2025-03-01)

Microvascular dysfunction in a murine model of Alzheimer’s disease using intravital microscopy
by: Danielle Sidsworth, et al.
Published: (2025-02-01)

Cerebrospinal fluid tau, neurogranin, and neurofilament light in Alzheimer's disease
by: Niklas Mattsson, et al.
Published: (2016-08-01)

Editorial: Neurodegeneration and cognitive impairment after traumatic brain injury
by: Tao Liu, et al.
Published: (2025-01-01)

Synaptic markers are associated with cognitive decline after accounting for amyloid burden among an at-risk Alzheimer’s disease cohort
by: Elizabeth M. Planalp, et al.
Published: (2025-06-01)

The effect of curcumin supplementation on cognitive function: an updated systematic review and meta-analysis
by: Wenlong Wang, et al.
Published: (2025-04-01)

Association of neurodegeneration, cognitive impairment, and short stature in Down syndrome; Could proinflammatory cytokines be the common factor?
by: Ghazaleh Sadeghi, et al.
Published: (2025-05-01)

The association between sleep quality and cognitive impairment among a multi-ethnic population of middle-aged and older adults in Western China: a multi-center cross-sectional study
by: Yuexia Hu, et al.
Published: (2025-04-01)

Thyroid Hormone Supplementation Restores Cognitive Deficit, Insulin Signaling, and Neuroinflammation in the Hippocampus of a Sporadic Alzheimer’s-like Disease Rat Model
by: Paulina Sepúlveda, et al.
Published: (2024-10-01)

A retrospective study on blood microbiota as a marker for cognitive decline: implications for detecting Alzheimer’s disease and amnestic mild cognitive impairment in Republic of Korea
by: Youngchan Park, et al.
Published: (2025-04-01)

Nature's neuroprotector: Honokiol and its promise for Alzheimer's and Parkinson's
by: Ahsas Goyal, et al.
Published: (2025-03-01)

Tooth loss impairs cognitive function in SAMP8 mice by aggravating pyroptosis of microglia via the cGAS/STING pathway
by: Xu Sun, et al.
Published: (2025-08-01)