Clinical case of successful application of photodynamic therapy in advanced vulvar cancer
A significant therapeutic effect of photodynamic therapy (PDT) is shown in a patient with extensive vulvar cancer after ineffective surgical and chemoradiotherapy. During the year, three courses of local PDT with a photosensitizer based on chlorin e6 were carried out. The photosensitizer was admin...
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| Format: | Article |
| Language: | Russian |
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Non-profit partnership for development of domestic photodynamic therapy and photodiagnosis "Russian Photodynamic Association"
2023-10-01
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| Series: | Biomedical Photonics |
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| Online Access: | https://www.pdt-journal.com/jour/article/view/605 |
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| author | N. A. Shanazarov T. G. Grishachevа G. S. Aldabergen S. B. Smailova Zh. Zh. Salmaganbetova |
| author_facet | N. A. Shanazarov T. G. Grishachevа G. S. Aldabergen S. B. Smailova Zh. Zh. Salmaganbetova |
| author_sort | N. A. Shanazarov |
| collection | DOAJ |
| description | A significant therapeutic effect of photodynamic therapy (PDT) is shown in a patient with extensive vulvar cancer after ineffective surgical and chemoradiotherapy. During the year, three courses of local PDT with a photosensitizer based on chlorin e6 were carried out. The photosensitizer was administered intravenously three hours before irradiation at a dose of 1.2 mg/kg. For laser irradiation (662 nm) of the vulvar tumor, a light guide for external irradiation was used: the power density was 0.2 W/cm2, the light dose was from 100 to 250 J/cm2. As a result of treatment, tumor regression and stable remission are observed. The patient remains under observation. |
| format | Article |
| id | doaj-art-b0ad7e521abb4768ae31308e9bd8c8af |
| institution | DOAJ |
| issn | 2413-9432 |
| language | Russian |
| publishDate | 2023-10-01 |
| publisher | Non-profit partnership for development of domestic photodynamic therapy and photodiagnosis "Russian Photodynamic Association" |
| record_format | Article |
| series | Biomedical Photonics |
| spelling | doaj-art-b0ad7e521abb4768ae31308e9bd8c8af2025-08-20T03:00:54ZrusNon-profit partnership for development of domestic photodynamic therapy and photodiagnosis "Russian Photodynamic Association"Biomedical Photonics2413-94322023-10-01123212410.24931/2413-9432-2023-12-3-21-24280Clinical case of successful application of photodynamic therapy in advanced vulvar cancerN. A. Shanazarov0T. G. Grishachevа1G. S. Aldabergen2S. B. Smailova3Zh. Zh. Salmaganbetova4Medical Center Hospital of the President’s Affairs Administration of the Republic of KazakhstanFirst St. Petersburg State Medical University named after I.I. acad. I.P. PavlovaMedical Center Hospital of the President’s Affairs Administration of the Republic of KazakhstanMedical Center Hospital of the President’s Affairs Administration of the Republic of KazakhstanMedical Center Hospital of the President’s Affairs Administration of the Republic of KazakhstanA significant therapeutic effect of photodynamic therapy (PDT) is shown in a patient with extensive vulvar cancer after ineffective surgical and chemoradiotherapy. During the year, three courses of local PDT with a photosensitizer based on chlorin e6 were carried out. The photosensitizer was administered intravenously three hours before irradiation at a dose of 1.2 mg/kg. For laser irradiation (662 nm) of the vulvar tumor, a light guide for external irradiation was used: the power density was 0.2 W/cm2, the light dose was from 100 to 250 J/cm2. As a result of treatment, tumor regression and stable remission are observed. The patient remains under observation.https://www.pdt-journal.com/jour/article/view/605vulvar cancerlocal photodynamic therapyclinical casephotolon |
| spellingShingle | N. A. Shanazarov T. G. Grishachevа G. S. Aldabergen S. B. Smailova Zh. Zh. Salmaganbetova Clinical case of successful application of photodynamic therapy in advanced vulvar cancer Biomedical Photonics vulvar cancer local photodynamic therapy clinical case photolon |
| title | Clinical case of successful application of photodynamic therapy in advanced vulvar cancer |
| title_full | Clinical case of successful application of photodynamic therapy in advanced vulvar cancer |
| title_fullStr | Clinical case of successful application of photodynamic therapy in advanced vulvar cancer |
| title_full_unstemmed | Clinical case of successful application of photodynamic therapy in advanced vulvar cancer |
| title_short | Clinical case of successful application of photodynamic therapy in advanced vulvar cancer |
| title_sort | clinical case of successful application of photodynamic therapy in advanced vulvar cancer |
| topic | vulvar cancer local photodynamic therapy clinical case photolon |
| url | https://www.pdt-journal.com/jour/article/view/605 |
| work_keys_str_mv | AT nashanazarov clinicalcaseofsuccessfulapplicationofphotodynamictherapyinadvancedvulvarcancer AT tggrishacheva clinicalcaseofsuccessfulapplicationofphotodynamictherapyinadvancedvulvarcancer AT gsaldabergen clinicalcaseofsuccessfulapplicationofphotodynamictherapyinadvancedvulvarcancer AT sbsmailova clinicalcaseofsuccessfulapplicationofphotodynamictherapyinadvancedvulvarcancer AT zhzhsalmaganbetova clinicalcaseofsuccessfulapplicationofphotodynamictherapyinadvancedvulvarcancer |