Clinical case of successful application of photodynamic therapy in advanced vulvar cancer

A significant  therapeutic effect of photodynamic  therapy (PDT) is shown in a patient with extensive vulvar cancer after ineffective surgical and chemoradiotherapy. During the year, three courses of local PDT with a photosensitizer based on chlorin e6 were carried out. The photosensitizer was admin...

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Bibliographic Details
Main Authors: N. A. Shanazarov, T. G. Grishachevа, G. S. Aldabergen, S. B. Smailova, Zh. Zh. Salmaganbetova
Format: Article
Language:Russian
Published: Non-profit partnership for development of domestic photodynamic therapy and photodiagnosis "Russian Photodynamic Association" 2023-10-01
Series:Biomedical Photonics
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Online Access:https://www.pdt-journal.com/jour/article/view/605
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Summary:A significant  therapeutic effect of photodynamic  therapy (PDT) is shown in a patient with extensive vulvar cancer after ineffective surgical and chemoradiotherapy. During the year, three courses of local PDT with a photosensitizer based on chlorin e6 were carried out. The photosensitizer was administered intravenously three hours before irradiation at a dose of 1.2 mg/kg. For laser irradiation (662 nm) of the vulvar tumor, a light guide for external irradiation was used: the power density was 0.2 W/cm2, the light dose was from 100 to 250 J/cm2. As a result of treatment, tumor regression and stable remission are observed. The patient remains under observation.
ISSN:2413-9432