Omega-3 polyunsaturated fatty acids in atrial fibrillation prevention after coronary bypass surgery

Aim. To assess omega-3-polyunsaturated fatty acids (w-3-PUFA) effects on atrial arrhythmogenicity in patients with coronary heart disease, who underwent coronary bypass surgery (CBS). Material and methods. In total, 50 patients, who underwent CBS, were examined. All participants were divided into tw...

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Main Author: B. A. Tatarsky
Format: Article
Language:Russian
Published: «SILICEA-POLIGRAF» LLC 2007-04-01
Series:Кардиоваскулярная терапия и профилактика
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Online Access:https://cardiovascular.elpub.ru/jour/article/view/1192
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author B. A. Tatarsky
author_facet B. A. Tatarsky
author_sort B. A. Tatarsky
collection DOAJ
description Aim. To assess omega-3-polyunsaturated fatty acids (w-3-PUFA) effects on atrial arrhythmogenicity in patients with coronary heart disease, who underwent coronary bypass surgery (CBS). Material and methods. In total, 50 patients, who underwent CBS, were examined. All participants were divided into two groups. Group I included 25 patients with atrial fibrillation (AF) episodes in anamnesis, who were administered w-3-PUFA (2 g/d) one week before and 7 days after CBS. Group II, control group, included 25 patients without AF in anamnesis, who did not receive w-3-PUFA. Atrial conduction abnormalities were registered by non-invasive, high-definition transesophageal electrocardiography. Results. In Group II, 7 AF cases (28%) were registered during early post-CBS period. AF paroxysm incidence was maximal in the first two days after CBS. In Group I, AF paroxysms were registered in 4 patients (16%), on Day 2-3 after CBS. Clinical symptoms were less severe in Group I than in Group II: in the former, two patients had asymptomatic AF episodes. No AF cases required cardioversion, terminating spontaneously. Group I patients demonstrated increased right and left atrium conductivity. Conclusion. In patients with post4CBS AF risk, w-3-PUFA therapy was associated with arrhythmia risk reduction, pontaneously terminating AF episodes, and less severe hemodynamic disturbances. Adding w-3-PUFA to standard therapy is effective and safe in CBS patients.
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spelling doaj-art-b0a2f9a3d3dc4f56824d7b387e1dd80f2025-08-20T03:57:17Zrus«SILICEA-POLIGRAF» LLCКардиоваскулярная терапия и профилактика1728-88002619-01252007-04-01625258904Omega-3 polyunsaturated fatty acids in atrial fibrillation prevention after coronary bypass surgeryB. A. Tatarsky0V.A. Almazov Research Institute of Cardiology, Federal State Agency for Health and Social Development. St. PetersburgAim. To assess omega-3-polyunsaturated fatty acids (w-3-PUFA) effects on atrial arrhythmogenicity in patients with coronary heart disease, who underwent coronary bypass surgery (CBS). Material and methods. In total, 50 patients, who underwent CBS, were examined. All participants were divided into two groups. Group I included 25 patients with atrial fibrillation (AF) episodes in anamnesis, who were administered w-3-PUFA (2 g/d) one week before and 7 days after CBS. Group II, control group, included 25 patients without AF in anamnesis, who did not receive w-3-PUFA. Atrial conduction abnormalities were registered by non-invasive, high-definition transesophageal electrocardiography. Results. In Group II, 7 AF cases (28%) were registered during early post-CBS period. AF paroxysm incidence was maximal in the first two days after CBS. In Group I, AF paroxysms were registered in 4 patients (16%), on Day 2-3 after CBS. Clinical symptoms were less severe in Group I than in Group II: in the former, two patients had asymptomatic AF episodes. No AF cases required cardioversion, terminating spontaneously. Group I patients demonstrated increased right and left atrium conductivity. Conclusion. In patients with post4CBS AF risk, w-3-PUFA therapy was associated with arrhythmia risk reduction, pontaneously terminating AF episodes, and less severe hemodynamic disturbances. Adding w-3-PUFA to standard therapy is effective and safe in CBS patients.https://cardiovascular.elpub.ru/jour/article/view/1192ω-3-polyunsaturated fatty acidscoronary heart diseasecoronary bypass surgerypost-surgery atrial fibrillation
spellingShingle B. A. Tatarsky
Omega-3 polyunsaturated fatty acids in atrial fibrillation prevention after coronary bypass surgery
Кардиоваскулярная терапия и профилактика
ω-3-polyunsaturated fatty acids
coronary heart disease
coronary bypass surgery
post-surgery atrial fibrillation
title Omega-3 polyunsaturated fatty acids in atrial fibrillation prevention after coronary bypass surgery
title_full Omega-3 polyunsaturated fatty acids in atrial fibrillation prevention after coronary bypass surgery
title_fullStr Omega-3 polyunsaturated fatty acids in atrial fibrillation prevention after coronary bypass surgery
title_full_unstemmed Omega-3 polyunsaturated fatty acids in atrial fibrillation prevention after coronary bypass surgery
title_short Omega-3 polyunsaturated fatty acids in atrial fibrillation prevention after coronary bypass surgery
title_sort omega 3 polyunsaturated fatty acids in atrial fibrillation prevention after coronary bypass surgery
topic ω-3-polyunsaturated fatty acids
coronary heart disease
coronary bypass surgery
post-surgery atrial fibrillation
url https://cardiovascular.elpub.ru/jour/article/view/1192
work_keys_str_mv AT batatarsky omega3polyunsaturatedfattyacidsinatrialfibrillationpreventionaftercoronarybypasssurgery