Supplementation of sodium alginate-coated Clostridium butyricum after cottonseed protein concentrate replacement of fishmeal can improve growth, immunity, and intestinal health in Litopenaeus vannamei

The present study evaluated the effects of supplementation with sodium alginate-coated Clostridium butyricum (SACB) on growth, immune response, and intestinal health of Litopenaeus vannamei following the replacement of fishmeal with cottonseed protein concentrate (CPC). The freeze-drying method was...

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Main Authors: Qi Wang, Depeng Fan, Yadong Hu, Hongyu Liu, Beiping Tan, Shiwei Xie, Qiang Chen
Format: Article
Language:English
Published: Elsevier 2024-12-01
Series:Aquaculture Reports
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Online Access:http://www.sciencedirect.com/science/article/pii/S2352513424006215
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author Qi Wang
Depeng Fan
Yadong Hu
Hongyu Liu
Beiping Tan
Shiwei Xie
Qiang Chen
author_facet Qi Wang
Depeng Fan
Yadong Hu
Hongyu Liu
Beiping Tan
Shiwei Xie
Qiang Chen
author_sort Qi Wang
collection DOAJ
description The present study evaluated the effects of supplementation with sodium alginate-coated Clostridium butyricum (SACB) on growth, immune response, and intestinal health of Litopenaeus vannamei following the replacement of fishmeal with cottonseed protein concentrate (CPC). The freeze-drying method was used for bacterial agent preparation, with the optimal ratio of freeze-dried protectant being 15 % skimmed milk, 12 % β-cyclodextrin, 8 % glucose, and 0.5 % dipotassium hydrogen phosphate. Six isonitrogenous and isolipid diets were formulated, with one serving as the control group (CG, 25 % fishmeal content). The remaining five diets were formulated as fishmeal replacement groups (CPC replacing 40 % of fishmeal). The content of SACB (5.1 × 108 CFU/g) in the alternative groups were 0 % (SACB0), 0.06 % (SACB1), 0.24 % (SACB2), 0.96 % (SACB3) and 3.84 % (SACB4), respectively. The results showed that SACB improved the growth performance (P > 0.05). Malondialdehyde content was significantly inhibited in hepatopancreas after SACB addition (P < 0.01). In the SACB3 group, intestinal trypsin, amylase, and lipase activities were remarkably enhanced (P < 0.05). The alpha diversity index was significantly higher in the SACB3 group (P < 0.001). LEfSe analysis showed that the relative abundance of beneficial bacteria such as Lactobacillus_murinus, Lactobacillus_johnsonii_FI9785, and Ruminiclostridium_5 increased in the SACB3 group (P < 0.05). Propionic and butyric acid contents were significantly higher in the SACB3 group (P < 0.05). The relative expression of genes including phenoloxidase, relish, penaeidin-3a, and crustins was significantly upregulated in the SACB3 and SACB4 groups (P < 0.05). Contents of total essential amino acids, total non-essential amino acids, and total amino acids in muscles were significantly higher in SACB3 and SACB4 groups (P < 0.05). In summary, suitable SACB improved shrimp growth, immune response, intestinal short-chain fatty acids, and muscle amino acids. The optimum SACB addition of 1.96 % was determined through binary regression analysis of specific growth rate.
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spelling doaj-art-b094843722074ee080d7325aa5ed276d2025-08-20T02:38:45ZengElsevierAquaculture Reports2352-51342024-12-013910253310.1016/j.aqrep.2024.102533Supplementation of sodium alginate-coated Clostridium butyricum after cottonseed protein concentrate replacement of fishmeal can improve growth, immunity, and intestinal health in Litopenaeus vannameiQi Wang0Depeng Fan1Yadong Hu2Hongyu Liu3Beiping Tan4Shiwei Xie5Qiang Chen6Laboratory of Aquatic Animal Nutrition and Feed, Fisheries College, Guangdong Ocean University, Zhanjiang 524025, PR China; Aquatic Animals Precision Nutrition and High Efficiency Feed Engineering Research Centre of Guangdong Province, Zhanjiang, Guangdong, PR China; Key Laboratory of Aquatic, Livestock and Poultry Feed Science and Technology in South China, Ministry of Agriculture, Zhanjiang 524025, PR China; Bio-Form Biotechnology (Guangdong) Co., Ltd., Foshan 528200, PR ChinaBio-Form Biotechnology (Guangdong) Co., Ltd., Foshan 528200, PR ChinaBio-Form Biotechnology (Guangdong) Co., Ltd., Foshan 528200, PR ChinaLaboratory of Aquatic Animal Nutrition and Feed, Fisheries College, Guangdong Ocean University, Zhanjiang 524025, PR China; Aquatic Animals Precision Nutrition and High Efficiency Feed Engineering Research Centre of Guangdong Province, Zhanjiang, Guangdong, PR China; Key Laboratory of Aquatic, Livestock and Poultry Feed Science and Technology in South China, Ministry of Agriculture, Zhanjiang 524025, PR China; Correspondence to: Laboratory of Aquatic Animal Nutrition and Feed, Fisheries College, Guangdong Ocean University, Zhanjiang 524088, PR China.Laboratory of Aquatic Animal Nutrition and Feed, Fisheries College, Guangdong Ocean University, Zhanjiang 524025, PR China; Aquatic Animals Precision Nutrition and High Efficiency Feed Engineering Research Centre of Guangdong Province, Zhanjiang, Guangdong, PR China; Key Laboratory of Aquatic, Livestock and Poultry Feed Science and Technology in South China, Ministry of Agriculture, Zhanjiang 524025, PR ChinaLaboratory of Aquatic Animal Nutrition and Feed, Fisheries College, Guangdong Ocean University, Zhanjiang 524025, PR China; Aquatic Animals Precision Nutrition and High Efficiency Feed Engineering Research Centre of Guangdong Province, Zhanjiang, Guangdong, PR China; Key Laboratory of Aquatic, Livestock and Poultry Feed Science and Technology in South China, Ministry of Agriculture, Zhanjiang 524025, PR ChinaLaboratory of Aquatic Animal Nutrition and Feed, Fisheries College, Guangdong Ocean University, Zhanjiang 524025, PR China; Aquatic Animals Precision Nutrition and High Efficiency Feed Engineering Research Centre of Guangdong Province, Zhanjiang, Guangdong, PR China; Key Laboratory of Aquatic, Livestock and Poultry Feed Science and Technology in South China, Ministry of Agriculture, Zhanjiang 524025, PR China; Bai Yang Industrial Investment Group Co., Ltd., Nanning 530000, PR ChinaThe present study evaluated the effects of supplementation with sodium alginate-coated Clostridium butyricum (SACB) on growth, immune response, and intestinal health of Litopenaeus vannamei following the replacement of fishmeal with cottonseed protein concentrate (CPC). The freeze-drying method was used for bacterial agent preparation, with the optimal ratio of freeze-dried protectant being 15 % skimmed milk, 12 % β-cyclodextrin, 8 % glucose, and 0.5 % dipotassium hydrogen phosphate. Six isonitrogenous and isolipid diets were formulated, with one serving as the control group (CG, 25 % fishmeal content). The remaining five diets were formulated as fishmeal replacement groups (CPC replacing 40 % of fishmeal). The content of SACB (5.1 × 108 CFU/g) in the alternative groups were 0 % (SACB0), 0.06 % (SACB1), 0.24 % (SACB2), 0.96 % (SACB3) and 3.84 % (SACB4), respectively. The results showed that SACB improved the growth performance (P > 0.05). Malondialdehyde content was significantly inhibited in hepatopancreas after SACB addition (P < 0.01). In the SACB3 group, intestinal trypsin, amylase, and lipase activities were remarkably enhanced (P < 0.05). The alpha diversity index was significantly higher in the SACB3 group (P < 0.001). LEfSe analysis showed that the relative abundance of beneficial bacteria such as Lactobacillus_murinus, Lactobacillus_johnsonii_FI9785, and Ruminiclostridium_5 increased in the SACB3 group (P < 0.05). Propionic and butyric acid contents were significantly higher in the SACB3 group (P < 0.05). The relative expression of genes including phenoloxidase, relish, penaeidin-3a, and crustins was significantly upregulated in the SACB3 and SACB4 groups (P < 0.05). Contents of total essential amino acids, total non-essential amino acids, and total amino acids in muscles were significantly higher in SACB3 and SACB4 groups (P < 0.05). In summary, suitable SACB improved shrimp growth, immune response, intestinal short-chain fatty acids, and muscle amino acids. The optimum SACB addition of 1.96 % was determined through binary regression analysis of specific growth rate.http://www.sciencedirect.com/science/article/pii/S2352513424006215Cottonseed protein concentrateClostridium butyricumLitopenaeus vannameiImmunityShort-chain fatty acid
spellingShingle Qi Wang
Depeng Fan
Yadong Hu
Hongyu Liu
Beiping Tan
Shiwei Xie
Qiang Chen
Supplementation of sodium alginate-coated Clostridium butyricum after cottonseed protein concentrate replacement of fishmeal can improve growth, immunity, and intestinal health in Litopenaeus vannamei
Aquaculture Reports
Cottonseed protein concentrate
Clostridium butyricum
Litopenaeus vannamei
Immunity
Short-chain fatty acid
title Supplementation of sodium alginate-coated Clostridium butyricum after cottonseed protein concentrate replacement of fishmeal can improve growth, immunity, and intestinal health in Litopenaeus vannamei
title_full Supplementation of sodium alginate-coated Clostridium butyricum after cottonseed protein concentrate replacement of fishmeal can improve growth, immunity, and intestinal health in Litopenaeus vannamei
title_fullStr Supplementation of sodium alginate-coated Clostridium butyricum after cottonseed protein concentrate replacement of fishmeal can improve growth, immunity, and intestinal health in Litopenaeus vannamei
title_full_unstemmed Supplementation of sodium alginate-coated Clostridium butyricum after cottonseed protein concentrate replacement of fishmeal can improve growth, immunity, and intestinal health in Litopenaeus vannamei
title_short Supplementation of sodium alginate-coated Clostridium butyricum after cottonseed protein concentrate replacement of fishmeal can improve growth, immunity, and intestinal health in Litopenaeus vannamei
title_sort supplementation of sodium alginate coated clostridium butyricum after cottonseed protein concentrate replacement of fishmeal can improve growth immunity and intestinal health in litopenaeus vannamei
topic Cottonseed protein concentrate
Clostridium butyricum
Litopenaeus vannamei
Immunity
Short-chain fatty acid
url http://www.sciencedirect.com/science/article/pii/S2352513424006215
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