Association of Endothelin-Converting Enzyme and Endothelin-1 Gene Polymorphisms with Essential Hypertension in Malay Ethnics

Objectives. Endothelin-1 (ET-1), the most potent endogenous vasoconstrictor, generated by enzymatic cleavage catalyzed by an endothelin-converting enzyme (ECE), plays a significant role in the regulation of hypertension. Methods. This study investigates the effect of endothelin-1 (Lys198Asn/rs5370)...

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Bibliographic Details
Main Authors: Elnaz Salim, Vasudevan Ramachandran, Neda Ansari, Patimah Ismail, Mohd Hazmi Mohamed, Nur Afiqah Mohamad, Liyana Najwa Inche Mat
Format: Article
Language:English
Published: Wiley 2022-01-01
Series:Genetics Research
Online Access:http://dx.doi.org/10.1155/2022/9129960
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