Gallic Acid Alleviates Acetaminophen-Induced Acute Liver Injury by Regulating Inflammatory and Oxidative Stress Signaling Proteins

Gallic Acid Alleviates Acetaminophen-Induced Acute Liver Injury by Regulating Inflammatory and Oxidative Stress Signaling Proteins

Acetaminophen (APAP) overdose is a major cause of drug-induced liver injury (DILI) globally, which necessitates effective therapies. Gallic acid (GA), a naturally abundant polyphenol, possesses potent antioxidant and anti-inflammatory properties that may overcome the limitations of N-acetylcysteine...

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Bibliographic Details
Main Authors: Jing Zhao, Yuan Zhao, Shuzhe Song, Sai Zhang, Guodong Yang, Yan Qiu, Weishun Tian
Format: Article
Language:English
Published: MDPI AG 2025-07-01
Series:Antioxidants
Subjects:
gallic acid
APAP
acute liver injury
oxidative stress
inflammation
Online Access:https://www.mdpi.com/2076-3921/14/7/860
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