CHIRP-Seq: FOXP2 transcriptional targets in zebra finch brain include numerous speech and language-related genes

Abstract Background Vocal learning is a rare, convergent trait that is fundamental to both human speech and birdsong. The Forkhead Box P2 (FOXP2) transcription factor appears necessary for both types of learned signals, as human mutations in FOXP2 result in speech deficits, and disrupting its expres...

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Main Authors: Gregory L. Gedman, Todd H. Kimball, Lee L. Atkinson, Daniella Factor, Gabriela Vojtova, Madza Farias-Virgens, Timothy F. Wright, Stephanie A. White
Format: Article
Language:English
Published: BMC 2025-04-01
Series:BMC Neuroscience
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Online Access:https://doi.org/10.1186/s12868-025-00948-6
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