Synthesis and DFT Calculation of a New Series of Enaminones based on 3-amino Coumarin

In this paper, the synthesis of various enaminones from the reaction of 3-aminocoumarin and ethyl-2,4-dioxo-4-arylbutanoate in the presence of p-toluene sulfonic acid is reported. The reaction was examined under different solvents and catalytic systems, which clearly proved the importance of acidic...

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Main Authors: Pegah Nouraie, Shahram Moradi Dehaghi, Alireza Foroumadi
Format: Article
Language:English
Published: University of Tehran 2020-09-01
Series:Journal of Sciences, Islamic Republic of Iran
Subjects:
Online Access:https://jsciences.ut.ac.ir/article_76455_bf744fd16b0c53749e3353009891fe97.pdf
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author Pegah Nouraie
Shahram Moradi Dehaghi
Alireza Foroumadi
author_facet Pegah Nouraie
Shahram Moradi Dehaghi
Alireza Foroumadi
author_sort Pegah Nouraie
collection DOAJ
description In this paper, the synthesis of various enaminones from the reaction of 3-aminocoumarin and ethyl-2,4-dioxo-4-arylbutanoate in the presence of p-toluene sulfonic acid is reported. The reaction was examined under different solvents and catalytic systems, which clearly proved the importance of acidic catalyst in this organic transformation. This work was also accompanied by density functional theory (DFT) studies to justify the formation of final products.
format Article
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institution Kabale University
issn 1016-1104
2345-6914
language English
publishDate 2020-09-01
publisher University of Tehran
record_format Article
series Journal of Sciences, Islamic Republic of Iran
spelling doaj-art-b075d7621b924e148feba4e375f6ce712025-08-20T03:53:51ZengUniversity of TehranJournal of Sciences, Islamic Republic of Iran1016-11042345-69142020-09-0131321322010.22059/jsciences.2020.284918.100742576455Synthesis and DFT Calculation of a New Series of Enaminones based on 3-amino CoumarinPegah Nouraie0Shahram Moradi Dehaghi1Alireza Foroumadi2Tehran North Branch, Islamic Azad UniversityTehran North Branch, Islamic Azad UniversityTehran University of Medical SciencesIn this paper, the synthesis of various enaminones from the reaction of 3-aminocoumarin and ethyl-2,4-dioxo-4-arylbutanoate in the presence of p-toluene sulfonic acid is reported. The reaction was examined under different solvents and catalytic systems, which clearly proved the importance of acidic catalyst in this organic transformation. This work was also accompanied by density functional theory (DFT) studies to justify the formation of final products.https://jsciences.ut.ac.ir/article_76455_bf744fd16b0c53749e3353009891fe97.pdf3-aminocoumarinenaminonesdft studies
spellingShingle Pegah Nouraie
Shahram Moradi Dehaghi
Alireza Foroumadi
Synthesis and DFT Calculation of a New Series of Enaminones based on 3-amino Coumarin
Journal of Sciences, Islamic Republic of Iran
3-aminocoumarin
enaminones
dft studies
title Synthesis and DFT Calculation of a New Series of Enaminones based on 3-amino Coumarin
title_full Synthesis and DFT Calculation of a New Series of Enaminones based on 3-amino Coumarin
title_fullStr Synthesis and DFT Calculation of a New Series of Enaminones based on 3-amino Coumarin
title_full_unstemmed Synthesis and DFT Calculation of a New Series of Enaminones based on 3-amino Coumarin
title_short Synthesis and DFT Calculation of a New Series of Enaminones based on 3-amino Coumarin
title_sort synthesis and dft calculation of a new series of enaminones based on 3 amino coumarin
topic 3-aminocoumarin
enaminones
dft studies
url https://jsciences.ut.ac.ir/article_76455_bf744fd16b0c53749e3353009891fe97.pdf
work_keys_str_mv AT pegahnouraie synthesisanddftcalculationofanewseriesofenaminonesbasedon3aminocoumarin
AT shahrammoradidehaghi synthesisanddftcalculationofanewseriesofenaminonesbasedon3aminocoumarin
AT alirezaforoumadi synthesisanddftcalculationofanewseriesofenaminonesbasedon3aminocoumarin