Risk Factors for Financial Toxicity in Patients With Pancreatic Cancer
ABSTRACT Background The increasing costs of cancer treatment impose a tremendous economic burden on patients and their families, adversely impacting their quality of life and patients' outcomes. Financial toxicity (FT), as a concept describing the economic burden on patients, is crucial to comp...
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| Main Authors: | , , , , , |
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| Format: | Article |
| Language: | English |
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Wiley
2025-04-01
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| Series: | Cancer Medicine |
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| Online Access: | https://doi.org/10.1002/cam4.70799 |
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| _version_ | 1850178992144908288 |
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| author | Jing Wang Jialu Cui Xiaoyuan Wang Zhihua Li Yang Liu Baoxin Shi |
| author_facet | Jing Wang Jialu Cui Xiaoyuan Wang Zhihua Li Yang Liu Baoxin Shi |
| author_sort | Jing Wang |
| collection | DOAJ |
| description | ABSTRACT Background The increasing costs of cancer treatment impose a tremendous economic burden on patients and their families, adversely impacting their quality of life and patients' outcomes. Financial toxicity (FT), as a concept describing the economic burden on patients, is crucial to comprehend the extent and determinants within specific contexts. Objective To understand the current status of FT among Chinese pancreatic cancer (PC) patients, identify risk factors for FT, and summarize the characteristics of high‐risk groups. Methods A cross‐sectional study involving 296 PC patients was conducted to investigate their general information, financial toxicity, quality of life, positive and negative affects, and social support. Univariate and multiple linear regression analyses were used to examine the correlation between FT and other variables. Results The PC patient's FT score was 54.27 ± 14.50, with 25.7% being forced to change their work status due to the disease diagnosis and 29.4% exhibiting economically related treatment nonadherence behaviors. Factor analysis showed financial toxicity associated with fewer household savings, more total out‐of‐pocket (OOP) costs, treatment nonadherence, unemployment, diminished positive affect, and insufficient social support. Conclusions FT was highly prevalent among PC patients and associated with factors such as household savings and total OOP costs. There was a need to identify and manage patients exhibiting high‐risk characteristics and to implement targeted interventions to mitigate their economic burden. |
| format | Article |
| id | doaj-art-b06f59cd4a2e46ccb5b47954d5453eb1 |
| institution | OA Journals |
| issn | 2045-7634 |
| language | English |
| publishDate | 2025-04-01 |
| publisher | Wiley |
| record_format | Article |
| series | Cancer Medicine |
| spelling | doaj-art-b06f59cd4a2e46ccb5b47954d5453eb12025-08-20T02:18:36ZengWileyCancer Medicine2045-76342025-04-01148n/an/a10.1002/cam4.70799Risk Factors for Financial Toxicity in Patients With Pancreatic CancerJing Wang0Jialu Cui1Xiaoyuan Wang2Zhihua Li3Yang Liu4Baoxin Shi5Hospice Care Research Center Tianjin Medical University Tianjin ChinaHospice Care Research Center Tianjin Medical University Tianjin ChinaTianJin Medical University Cancer Institute and Hospital Tianjin Medical University Tianjin ChinaTianJin Medical University Cancer Institute and Hospital Tianjin Medical University Tianjin ChinaTianJin Medical University Cancer Institute and Hospital Tianjin Medical University Tianjin ChinaHospice Care Research Center Tianjin Medical University Tianjin ChinaABSTRACT Background The increasing costs of cancer treatment impose a tremendous economic burden on patients and their families, adversely impacting their quality of life and patients' outcomes. Financial toxicity (FT), as a concept describing the economic burden on patients, is crucial to comprehend the extent and determinants within specific contexts. Objective To understand the current status of FT among Chinese pancreatic cancer (PC) patients, identify risk factors for FT, and summarize the characteristics of high‐risk groups. Methods A cross‐sectional study involving 296 PC patients was conducted to investigate their general information, financial toxicity, quality of life, positive and negative affects, and social support. Univariate and multiple linear regression analyses were used to examine the correlation between FT and other variables. Results The PC patient's FT score was 54.27 ± 14.50, with 25.7% being forced to change their work status due to the disease diagnosis and 29.4% exhibiting economically related treatment nonadherence behaviors. Factor analysis showed financial toxicity associated with fewer household savings, more total out‐of‐pocket (OOP) costs, treatment nonadherence, unemployment, diminished positive affect, and insufficient social support. Conclusions FT was highly prevalent among PC patients and associated with factors such as household savings and total OOP costs. There was a need to identify and manage patients exhibiting high‐risk characteristics and to implement targeted interventions to mitigate their economic burden.https://doi.org/10.1002/cam4.70799financial toxicitypancreatic cancerpsychological distressquality of lifesocial support |
| spellingShingle | Jing Wang Jialu Cui Xiaoyuan Wang Zhihua Li Yang Liu Baoxin Shi Risk Factors for Financial Toxicity in Patients With Pancreatic Cancer Cancer Medicine financial toxicity pancreatic cancer psychological distress quality of life social support |
| title | Risk Factors for Financial Toxicity in Patients With Pancreatic Cancer |
| title_full | Risk Factors for Financial Toxicity in Patients With Pancreatic Cancer |
| title_fullStr | Risk Factors for Financial Toxicity in Patients With Pancreatic Cancer |
| title_full_unstemmed | Risk Factors for Financial Toxicity in Patients With Pancreatic Cancer |
| title_short | Risk Factors for Financial Toxicity in Patients With Pancreatic Cancer |
| title_sort | risk factors for financial toxicity in patients with pancreatic cancer |
| topic | financial toxicity pancreatic cancer psychological distress quality of life social support |
| url | https://doi.org/10.1002/cam4.70799 |
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