Cost-effectiveness analysis of the Assessment of Burden of Chronic Conditions (ABCC) tool in primary care in the Netherlands

Objectives The increasing prevalence of chronic conditions and multimorbidity places a significant burden on patients and leads to increasing challenges for healthcare systems, especially in primary care. Recognising the multifaceted nature of chronic conditions, the Assessment of Burden of Chronic...

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Main Authors: Manuela A Joore, Esther A Boudewijns, Mascha Twellaar, Onno CP van Schayck, Merel L Kimman, Loraine HL Peters, Annerika HM Gidding-Slok, Lotte CEM Keijsers, Jean WM Muris
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Language:English
Published: BMJ Publishing Group 2025-06-01
Series:BMJ Open
Online Access:https://bmjopen.bmj.com/content/15/6/e099762.full
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author Manuela A Joore
Esther A Boudewijns
Mascha Twellaar
Onno CP van Schayck
Merel L Kimman
Loraine HL Peters
Annerika HM Gidding-Slok
Lotte CEM Keijsers
Jean WM Muris
author_facet Manuela A Joore
Esther A Boudewijns
Mascha Twellaar
Onno CP van Schayck
Merel L Kimman
Loraine HL Peters
Annerika HM Gidding-Slok
Lotte CEM Keijsers
Jean WM Muris
author_sort Manuela A Joore
collection DOAJ
description Objectives The increasing prevalence of chronic conditions and multimorbidity places a significant burden on patients and leads to increasing challenges for healthcare systems, especially in primary care. Recognising the multifaceted nature of chronic conditions, the Assessment of Burden of Chronic Conditions (ABCC) tool was developed to support person-centred care, by facilitating shared decision-making and self-management. This study aims to evaluate the cost-effectiveness of the ABCC tool in primary care.Design and setting This cost-effectiveness analysis was conducted over 18 months alongside a clustered, two-arm quasi-experimental study in primary care in the Netherlands.Participants The study included 231 participants diagnosed with chronic obstructive pulmonary disease (COPD), asthma, type 2 diabetes mellitus (T2DM) and/or chronic heart failure (CHF). Of these, 173 were assigned to the intervention group and 58 to the control group.Interventions The intervention group was intended to incorporate the ABCC tool into routine consultations, while the control group had to continue care as usual.Outcome measures Outcomes were assessed from a societal perspective, including quality-adjusted life years (QALYs) derived via the EuroQol-5D-5L (EQ-5D-5L) questionnaire. Costs were measured using adapted versions of the Productivity Costs Questionnaire (PCQ) and Medical Consumption Questionnaire (MCQ). Sensitivity analyses (SAs) included a healthcare perspective, per-protocol analysis (to account for disruptions caused by COVID-19) and exclusion of home care costs (to address extreme outliers). Moreover, all analyses were performed for well-being-adjusted life years (WALYs), derived from the ICEpop CAPability measure for Adults (ICECAP-A) questionnaire.Results The ABCC tool was more expensive and effective than usual care, with an incremental cost-effectiveness ratio (ICER) of €64 525 per QALY and a 29% probability of cost-effectiveness. With the exception of the healthcare perspective, the SAs yielded more favourable outcomes in terms of cost-effectiveness, with ICERs (probability of cost-effectiveness) of €41 484 (31%), €8683 (58%) and €23 905 (48%) for a healthcare perspective, per-protocol analysis and exclusion of home care costs, respectively. Outcomes for QALY and WALY were comparable.Conclusion While the primary analysis suggested a relatively low probability of cost-effectiveness, the SAs showed higher probabilities. The per-protocol analysis suggested that the ABCC tool can be cost-effective when actually used.Trial registration number NCT04127383.
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spelling doaj-art-b06f4001e8f6490daed75483b0e95b6f2025-08-20T03:27:48ZengBMJ Publishing GroupBMJ Open2044-60552025-06-0115610.1136/bmjopen-2025-099762Cost-effectiveness analysis of the Assessment of Burden of Chronic Conditions (ABCC) tool in primary care in the NetherlandsManuela A Joore0Esther A Boudewijns1Mascha Twellaar2Onno CP van Schayck3Merel L Kimman4Loraine HL Peters5Annerika HM Gidding-Slok6Lotte CEM Keijsers7Jean WM Muris8Department of Clinical Epidemiology and Medical Technology Assessment (KEMTA), Maastricht University Medical Centre+ (MUMC+), Maastricht, The NetherlandsDepartment of Family Medicine, Care and Public Health Research Institute (CAPHRI), Maastricht University, Maastricht, The NetherlandsDepartment of Family Medicine, Care and Public Health Research Institute (CAPHRI), Maastricht University, Maastricht, The NetherlandsDepartment of Family Medicine, Care and Public Health Research Institute (CAPHRI), Maastricht University, Maastricht, The NetherlandsDepartment of Clinical Epidemiology and Medical Technology Assessment (KEMTA), Maastricht University Medical Centre+ (MUMC+), Maastricht, The NetherlandsDepartment of Family Medicine, Care and Public Health Research Institute (CAPHRI), Maastricht University, Maastricht, The NetherlandsDepartment of Family Medicine, Care and Public Health Research Institute (CAPHRI), Maastricht University, Maastricht, The NetherlandsDepartment of Family Medicine, Care and Public Health Research Institute (CAPHRI), Maastricht University, Maastricht, The NetherlandsDepartment of Family Medicine, Care and Public Health Research Institute (CAPHRI), Maastricht University, Maastricht, The NetherlandsObjectives The increasing prevalence of chronic conditions and multimorbidity places a significant burden on patients and leads to increasing challenges for healthcare systems, especially in primary care. Recognising the multifaceted nature of chronic conditions, the Assessment of Burden of Chronic Conditions (ABCC) tool was developed to support person-centred care, by facilitating shared decision-making and self-management. This study aims to evaluate the cost-effectiveness of the ABCC tool in primary care.Design and setting This cost-effectiveness analysis was conducted over 18 months alongside a clustered, two-arm quasi-experimental study in primary care in the Netherlands.Participants The study included 231 participants diagnosed with chronic obstructive pulmonary disease (COPD), asthma, type 2 diabetes mellitus (T2DM) and/or chronic heart failure (CHF). Of these, 173 were assigned to the intervention group and 58 to the control group.Interventions The intervention group was intended to incorporate the ABCC tool into routine consultations, while the control group had to continue care as usual.Outcome measures Outcomes were assessed from a societal perspective, including quality-adjusted life years (QALYs) derived via the EuroQol-5D-5L (EQ-5D-5L) questionnaire. Costs were measured using adapted versions of the Productivity Costs Questionnaire (PCQ) and Medical Consumption Questionnaire (MCQ). Sensitivity analyses (SAs) included a healthcare perspective, per-protocol analysis (to account for disruptions caused by COVID-19) and exclusion of home care costs (to address extreme outliers). Moreover, all analyses were performed for well-being-adjusted life years (WALYs), derived from the ICEpop CAPability measure for Adults (ICECAP-A) questionnaire.Results The ABCC tool was more expensive and effective than usual care, with an incremental cost-effectiveness ratio (ICER) of €64 525 per QALY and a 29% probability of cost-effectiveness. With the exception of the healthcare perspective, the SAs yielded more favourable outcomes in terms of cost-effectiveness, with ICERs (probability of cost-effectiveness) of €41 484 (31%), €8683 (58%) and €23 905 (48%) for a healthcare perspective, per-protocol analysis and exclusion of home care costs, respectively. Outcomes for QALY and WALY were comparable.Conclusion While the primary analysis suggested a relatively low probability of cost-effectiveness, the SAs showed higher probabilities. The per-protocol analysis suggested that the ABCC tool can be cost-effective when actually used.Trial registration number NCT04127383.https://bmjopen.bmj.com/content/15/6/e099762.full
spellingShingle Manuela A Joore
Esther A Boudewijns
Mascha Twellaar
Onno CP van Schayck
Merel L Kimman
Loraine HL Peters
Annerika HM Gidding-Slok
Lotte CEM Keijsers
Jean WM Muris
Cost-effectiveness analysis of the Assessment of Burden of Chronic Conditions (ABCC) tool in primary care in the Netherlands
BMJ Open
title Cost-effectiveness analysis of the Assessment of Burden of Chronic Conditions (ABCC) tool in primary care in the Netherlands
title_full Cost-effectiveness analysis of the Assessment of Burden of Chronic Conditions (ABCC) tool in primary care in the Netherlands
title_fullStr Cost-effectiveness analysis of the Assessment of Burden of Chronic Conditions (ABCC) tool in primary care in the Netherlands
title_full_unstemmed Cost-effectiveness analysis of the Assessment of Burden of Chronic Conditions (ABCC) tool in primary care in the Netherlands
title_short Cost-effectiveness analysis of the Assessment of Burden of Chronic Conditions (ABCC) tool in primary care in the Netherlands
title_sort cost effectiveness analysis of the assessment of burden of chronic conditions abcc tool in primary care in the netherlands
url https://bmjopen.bmj.com/content/15/6/e099762.full
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