Regenerated Oxidized Cellulose as a Sealant and Adhesive in Endoscopic Endonasal Skull Base Reconstruction

Introduction An ideal and long-lasting adhesive and sealant is essential during endoscopic endonasal skull-base surgery to hold the reconstruction intact and prevent cerebrospinal fluid (CSF) permeation until complete healing occurs. Fibrin glue is the most common material used. Regenerat...

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Main Authors: Ashwin Gajendran Vedhapoodi, Aravind Sabesan, Benazir Ferozkhan, Saravana Selvan Velmurugan, Venkatesan Rajarajan, Baskar Arukavur Radhakrishnan, Kanagaraman Prabhuraman, Bhuvaneswari Natarajan
Format: Article
Language:English
Published: Thieme Revinter Publicações Ltda. 2025-04-01
Series:International Archives of Otorhinolaryngology
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Online Access:http://www.thieme-connect.de/DOI/DOI?10.1055/s-0044-1788599
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author Ashwin Gajendran Vedhapoodi
Aravind Sabesan
Benazir Ferozkhan
Saravana Selvan Velmurugan
Venkatesan Rajarajan
Baskar Arukavur Radhakrishnan
Kanagaraman Prabhuraman
Bhuvaneswari Natarajan
author_facet Ashwin Gajendran Vedhapoodi
Aravind Sabesan
Benazir Ferozkhan
Saravana Selvan Velmurugan
Venkatesan Rajarajan
Baskar Arukavur Radhakrishnan
Kanagaraman Prabhuraman
Bhuvaneswari Natarajan
author_sort Ashwin Gajendran Vedhapoodi
collection DOAJ
description Introduction An ideal and long-lasting adhesive and sealant is essential during endoscopic endonasal skull-base surgery to hold the reconstruction intact and prevent cerebrospinal fluid (CSF) permeation until complete healing occurs. Fibrin glue is the most common material used. Regenerated oxidized cellulose (ROC) has not been mentioned in the literature as sealant and adhesive, and, hence, we intended to study this role.
format Article
id doaj-art-b06ed6cf39124fe18b3cd743b08b6cf7
institution OA Journals
issn 1809-9777
1809-4864
language English
publishDate 2025-04-01
publisher Thieme Revinter Publicações Ltda.
record_format Article
series International Archives of Otorhinolaryngology
spelling doaj-art-b06ed6cf39124fe18b3cd743b08b6cf72025-08-20T02:11:37ZengThieme Revinter Publicações Ltda.International Archives of Otorhinolaryngology1809-97771809-48642025-04-01290200101010.1055/s-0044-1788599Regenerated Oxidized Cellulose as a Sealant and Adhesive in Endoscopic Endonasal Skull Base ReconstructionAshwin Gajendran Vedhapoodi0https://orcid.org/0000-0001-8741-2689Aravind Sabesan1Benazir Ferozkhan2Saravana Selvan Velmurugan3Venkatesan Rajarajan4Baskar Arukavur Radhakrishnan5Kanagaraman Prabhuraman6Bhuvaneswari Natarajan7Department of Otorhinolaryngology, Head and Neck Surgery, Government Stanley Medical College, Chennai, Tamil Nadu, IndiaDepartment of Neurosurgery, Government Stanley Medical College, Chennai, Tamil Nadu, IndiaDepartment of Otorhinolaryngology, Head and Neck Surgery, Government Stanley Medical College, Chennai, Tamil Nadu, IndiaDepartment of Otorhinolaryngology, Madras Medical College, Chennai, Tamil Nadu, IndiaDepartment of Otorhinolaryngology, Head and Neck Surgery, Government Stanley Medical College, Chennai, Tamil Nadu, IndiaDepartment of Neurosurgery, Government Stanley Medical College, Chennai, Tamil Nadu, IndiaDepartment of Neurosurgery, Government Stanley Medical College, Chennai, Tamil Nadu, IndiaDepartment of Community Medicine, Sri Venkateswaraa Medical College Hospital and Research Centre, Puducherry, Tamil Nadu, India Introduction An ideal and long-lasting adhesive and sealant is essential during endoscopic endonasal skull-base surgery to hold the reconstruction intact and prevent cerebrospinal fluid (CSF) permeation until complete healing occurs. Fibrin glue is the most common material used. Regenerated oxidized cellulose (ROC) has not been mentioned in the literature as sealant and adhesive, and, hence, we intended to study this role.http://www.thieme-connect.de/DOI/DOI?10.1055/s-0044-1788599Surgicelregenerated oxidized celluloseCSF leaktissue sealanttissue adhesive
spellingShingle Ashwin Gajendran Vedhapoodi
Aravind Sabesan
Benazir Ferozkhan
Saravana Selvan Velmurugan
Venkatesan Rajarajan
Baskar Arukavur Radhakrishnan
Kanagaraman Prabhuraman
Bhuvaneswari Natarajan
Regenerated Oxidized Cellulose as a Sealant and Adhesive in Endoscopic Endonasal Skull Base Reconstruction
International Archives of Otorhinolaryngology
Surgicel
regenerated oxidized cellulose
CSF leak
tissue sealant
tissue adhesive
title Regenerated Oxidized Cellulose as a Sealant and Adhesive in Endoscopic Endonasal Skull Base Reconstruction
title_full Regenerated Oxidized Cellulose as a Sealant and Adhesive in Endoscopic Endonasal Skull Base Reconstruction
title_fullStr Regenerated Oxidized Cellulose as a Sealant and Adhesive in Endoscopic Endonasal Skull Base Reconstruction
title_full_unstemmed Regenerated Oxidized Cellulose as a Sealant and Adhesive in Endoscopic Endonasal Skull Base Reconstruction
title_short Regenerated Oxidized Cellulose as a Sealant and Adhesive in Endoscopic Endonasal Skull Base Reconstruction
title_sort regenerated oxidized cellulose as a sealant and adhesive in endoscopic endonasal skull base reconstruction
topic Surgicel
regenerated oxidized cellulose
CSF leak
tissue sealant
tissue adhesive
url http://www.thieme-connect.de/DOI/DOI?10.1055/s-0044-1788599
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