Experiences and perceptions about vaccines and reporting of adverse events following immunisation: a qualitative study among mothers in Northern Ghana

Background Immunisation is an essential and cost-effective way of preventing infectious diseases. The emergence of new diseases, including COVID-19, along with advancements in malaria vaccines, has potentially led to an increase in vaccinations, particularly among children under 5 years old in Afric...

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Main Authors: Daniel Weibel, Abraham Oduro, Miriam Sturkenboom, Nana Akosua Ansah, Samuel Tomilola Oladokun, Enyonam Duah, Patrick Ansah, Samuel Tamti Chatio
Format: Article
Language:English
Published: BMJ Publishing Group 2025-08-01
Series:BMJ Public Health
Online Access:https://bmjpublichealth.bmj.com/content/3/2/e001761.full
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author Daniel Weibel
Abraham Oduro
Miriam Sturkenboom
Nana Akosua Ansah
Samuel Tomilola Oladokun
Enyonam Duah
Patrick Ansah
Samuel Tamti Chatio
author_facet Daniel Weibel
Abraham Oduro
Miriam Sturkenboom
Nana Akosua Ansah
Samuel Tomilola Oladokun
Enyonam Duah
Patrick Ansah
Samuel Tamti Chatio
author_sort Daniel Weibel
collection DOAJ
description Background Immunisation is an essential and cost-effective way of preventing infectious diseases. The emergence of new diseases, including COVID-19, along with advancements in malaria vaccines, has potentially led to an increase in vaccinations, particularly among children under 5 years old in Africa. However, concerns about vaccine safety have led to a decline in trust and greater vaccine hesitancy, as evidenced by the low uptake of newly introduced vaccines like the pneumococcal vaccine-13 in Ghana.Adverse events following immunisation (AEFIs) may range from mild to severe and are of concern because vaccines are generally given to healthy people. To monitor vaccine safety, it is important that those who experience adverse events report to the nearest health facility, but compliance is low in Ghana. This study explored the knowledge and experiences of mothers in northern Ghana regarding vaccine safety and adverse event reporting procedures.Methods This cross-sectional exploratory study used a qualitative research design that involved 10 focus group discussions (FGDs) with mothers from 5 administrative regions in resource-limited Northern Ghana. Participants for the FGDs were selected through a purposive sampling method at childhood vaccination clinics. All the interviews were recorded, transcribed and coded into themes using QSR NVivo V.12 software to aid thematic content analysis.Results The results revealed that mothers understood the need for vaccinations, although some were unaware of the diseases that the vaccines protect against. Even though most mothers knew about the benefits of vaccinations, many expressed concerns about the pain and discomfort their children experienced during the process. Furthermore, they noted that the absence of responses from health workers following the reporting of AEFIs, the belief that adverse events are commonplace, and previous vaccination experiences all influenced AEFI reporting. The fear of serious adverse events such as paralysis, coupled with insufficient explanation of the benefits, may dissuade parents from allowing their children to receive vaccinations. The findings also revealed that mothers were not adequately informed about vaccines and the need for them to report adverse events.Conclusions Many individuals regard vaccines as an essential public health intervention for preventing diseases and their related complications. Public health agencies and healthcare providers ought to address concerns about vaccine adverse events by providing thorough education for mothers about vaccines and AEFI reporting.
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spelling doaj-art-b068f0aee5a24029aa37e18e3b04056d2025-08-20T04:02:33ZengBMJ Publishing GroupBMJ Public Health2753-42942025-08-013210.1136/bmjph-2024-001761Experiences and perceptions about vaccines and reporting of adverse events following immunisation: a qualitative study among mothers in Northern GhanaDaniel Weibel0Abraham Oduro1Miriam Sturkenboom2Nana Akosua Ansah3Samuel Tomilola Oladokun4Enyonam Duah5Patrick Ansah6Samuel Tamti Chatio7UMC, Utrecht, NetherlandsResearch and Development Division, Ghana Health Service, Accra, Ghanaassociate professorNavrongo Health Research Centre, Navrongo, GhanaNavrongo Health Research Centre, Navrongo, GhanaNavrongo Health Research Centre, Navrongo, GhanaNavrongo Health Research Centre, Navrongo, GhanaNavrongo Health Research Centre, Navrongo, GhanaBackground Immunisation is an essential and cost-effective way of preventing infectious diseases. The emergence of new diseases, including COVID-19, along with advancements in malaria vaccines, has potentially led to an increase in vaccinations, particularly among children under 5 years old in Africa. However, concerns about vaccine safety have led to a decline in trust and greater vaccine hesitancy, as evidenced by the low uptake of newly introduced vaccines like the pneumococcal vaccine-13 in Ghana.Adverse events following immunisation (AEFIs) may range from mild to severe and are of concern because vaccines are generally given to healthy people. To monitor vaccine safety, it is important that those who experience adverse events report to the nearest health facility, but compliance is low in Ghana. This study explored the knowledge and experiences of mothers in northern Ghana regarding vaccine safety and adverse event reporting procedures.Methods This cross-sectional exploratory study used a qualitative research design that involved 10 focus group discussions (FGDs) with mothers from 5 administrative regions in resource-limited Northern Ghana. Participants for the FGDs were selected through a purposive sampling method at childhood vaccination clinics. All the interviews were recorded, transcribed and coded into themes using QSR NVivo V.12 software to aid thematic content analysis.Results The results revealed that mothers understood the need for vaccinations, although some were unaware of the diseases that the vaccines protect against. Even though most mothers knew about the benefits of vaccinations, many expressed concerns about the pain and discomfort their children experienced during the process. Furthermore, they noted that the absence of responses from health workers following the reporting of AEFIs, the belief that adverse events are commonplace, and previous vaccination experiences all influenced AEFI reporting. The fear of serious adverse events such as paralysis, coupled with insufficient explanation of the benefits, may dissuade parents from allowing their children to receive vaccinations. The findings also revealed that mothers were not adequately informed about vaccines and the need for them to report adverse events.Conclusions Many individuals regard vaccines as an essential public health intervention for preventing diseases and their related complications. Public health agencies and healthcare providers ought to address concerns about vaccine adverse events by providing thorough education for mothers about vaccines and AEFI reporting.https://bmjpublichealth.bmj.com/content/3/2/e001761.full
spellingShingle Daniel Weibel
Abraham Oduro
Miriam Sturkenboom
Nana Akosua Ansah
Samuel Tomilola Oladokun
Enyonam Duah
Patrick Ansah
Samuel Tamti Chatio
Experiences and perceptions about vaccines and reporting of adverse events following immunisation: a qualitative study among mothers in Northern Ghana
BMJ Public Health
title Experiences and perceptions about vaccines and reporting of adverse events following immunisation: a qualitative study among mothers in Northern Ghana
title_full Experiences and perceptions about vaccines and reporting of adverse events following immunisation: a qualitative study among mothers in Northern Ghana
title_fullStr Experiences and perceptions about vaccines and reporting of adverse events following immunisation: a qualitative study among mothers in Northern Ghana
title_full_unstemmed Experiences and perceptions about vaccines and reporting of adverse events following immunisation: a qualitative study among mothers in Northern Ghana
title_short Experiences and perceptions about vaccines and reporting of adverse events following immunisation: a qualitative study among mothers in Northern Ghana
title_sort experiences and perceptions about vaccines and reporting of adverse events following immunisation a qualitative study among mothers in northern ghana
url https://bmjpublichealth.bmj.com/content/3/2/e001761.full
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