Intratumor heterogeneity related signature for clinical outcome and immunotherapy advantages in lung adenocarcinoma
Abstract Background Immunotherapy benefits shows discrepancy in different lung adenocarcinoma (LUAD) patients because of the intratumor heterogeneity (ITH). ITH favors tumor evolution and correlated with drug resistance. The genes mediating ITH in LUAD and their role in predicting prognosis and ther...
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| Main Authors: | , , |
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| Format: | Article |
| Language: | English |
| Published: |
Springer
2025-03-01
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| Series: | Discover Oncology |
| Subjects: | |
| Online Access: | https://doi.org/10.1007/s12672-025-02173-3 |
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