A novel chimpanzee adenovirus vector vaccine for protection against infectious bronchitis and Newcastle disease in chickens

A novel chimpanzee adenovirus vector vaccine for protection against infectious bronchitis and Newcastle disease in chickens

Abstract The development of effective poultry vaccines is crucial for maintaining flock health and productivity. In this study, we developed and evaluated a recombinant chimpanzee adenovirus vaccine (PAD-S1-HN) that simultaneously expresses the infectious bronchitis virus (IBV) spike subunit protein...

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Bibliographic Details
Main Authors: Chengyao Hou, Ruiqi Ni, Lijun Zhao, Wenjun Yan, Kailu Wang, Qinyuan Chu, Xinggui Chen, Hongning Wang, Xin Yang
Format: Article
Language:English
Published: BMC 2025-05-01
Series:Veterinary Research
Subjects:
nonreplicating chimpanzee adenovirus
bivalent vaccine
IBV S1 protein
NDV HN protein
poultry immunization
Online Access:https://doi.org/10.1186/s13567-025-01528-6
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