A Follow-Up Report of an Infant Born to a Mother Receiving Tamoxifen

Tamoxifen, an estrogen receptor antagonist, is contraindicated in pregnant women due to its teratogenic activity. In the present study, we report the case of an infant whose mother received tamoxifen for breast cancer while unaware of the pregnancy. The infant, born at 29 weeks and 6 days of gestati...

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Main Authors: Yuki Okada, Daisuke Hitaka, Takahiro Kido, Yu Kanai, Kumi Konishi, Kosuke Doki, Nobuko Katayama, Masato Homma, Yayoi Miyazono, Hidetoshi Takada
Format: Article
Language:English
Published: Wiley 2020-01-01
Series:Case Reports in Pediatrics
Online Access:http://dx.doi.org/10.1155/2020/2056756
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author Yuki Okada
Daisuke Hitaka
Takahiro Kido
Yu Kanai
Kumi Konishi
Kosuke Doki
Nobuko Katayama
Masato Homma
Yayoi Miyazono
Hidetoshi Takada
author_facet Yuki Okada
Daisuke Hitaka
Takahiro Kido
Yu Kanai
Kumi Konishi
Kosuke Doki
Nobuko Katayama
Masato Homma
Yayoi Miyazono
Hidetoshi Takada
author_sort Yuki Okada
collection DOAJ
description Tamoxifen, an estrogen receptor antagonist, is contraindicated in pregnant women due to its teratogenic activity. In the present study, we report the case of an infant whose mother received tamoxifen for breast cancer while unaware of the pregnancy. The infant, born at 29 weeks and 6 days of gestational age with a birth weight of 1664 g, had no congenital anomalies. This case presents detailed information on the development of an infant with placental transfer of tamoxifen. The infant has grown and developed normally throughout a 5-year follow-up period, but long-term vigilance continues.
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institution Kabale University
issn 2090-6803
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language English
publishDate 2020-01-01
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record_format Article
series Case Reports in Pediatrics
spelling doaj-art-b05de5d3576c4bab834239e679eaa2a12025-02-03T05:53:54ZengWileyCase Reports in Pediatrics2090-68032090-68112020-01-01202010.1155/2020/20567562056756A Follow-Up Report of an Infant Born to a Mother Receiving TamoxifenYuki Okada0Daisuke Hitaka1Takahiro Kido2Yu Kanai3Kumi Konishi4Kosuke Doki5Nobuko Katayama6Masato Homma7Yayoi Miyazono8Hidetoshi Takada9Department of Pediatrics, University of Tsukuba Hospital, Tsukuba, Ibaraki, JapanDepartment of Pediatrics, University of Tsukuba Hospital, Tsukuba, Ibaraki, JapanDepartment of Pediatrics, University of Tsukuba Hospital, Tsukuba, Ibaraki, JapanDepartment of Pediatrics, University of Tsukuba Hospital, Tsukuba, Ibaraki, JapanDepartment of Pharmacy, University of Tsukuba Hospital, Tsukuba, Ibaraki, JapanDepartment of Pharmacy, University of Tsukuba Hospital, Tsukuba, Ibaraki, JapanDepartment of Child Health, Seinan Medical Center Hospital, Sakai, Ibaraki, JapanDepartment of Pharmacy, University of Tsukuba Hospital, Tsukuba, Ibaraki, JapanDepartment of Pediatrics, University of Tsukuba Hospital, Tsukuba, Ibaraki, JapanDepartment of Pediatrics, University of Tsukuba Hospital, Tsukuba, Ibaraki, JapanTamoxifen, an estrogen receptor antagonist, is contraindicated in pregnant women due to its teratogenic activity. In the present study, we report the case of an infant whose mother received tamoxifen for breast cancer while unaware of the pregnancy. The infant, born at 29 weeks and 6 days of gestational age with a birth weight of 1664 g, had no congenital anomalies. This case presents detailed information on the development of an infant with placental transfer of tamoxifen. The infant has grown and developed normally throughout a 5-year follow-up period, but long-term vigilance continues.http://dx.doi.org/10.1155/2020/2056756
spellingShingle Yuki Okada
Daisuke Hitaka
Takahiro Kido
Yu Kanai
Kumi Konishi
Kosuke Doki
Nobuko Katayama
Masato Homma
Yayoi Miyazono
Hidetoshi Takada
A Follow-Up Report of an Infant Born to a Mother Receiving Tamoxifen
Case Reports in Pediatrics
title A Follow-Up Report of an Infant Born to a Mother Receiving Tamoxifen
title_full A Follow-Up Report of an Infant Born to a Mother Receiving Tamoxifen
title_fullStr A Follow-Up Report of an Infant Born to a Mother Receiving Tamoxifen
title_full_unstemmed A Follow-Up Report of an Infant Born to a Mother Receiving Tamoxifen
title_short A Follow-Up Report of an Infant Born to a Mother Receiving Tamoxifen
title_sort follow up report of an infant born to a mother receiving tamoxifen
url http://dx.doi.org/10.1155/2020/2056756
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