Influence of anti-Spike protein antibody levels on tocilizumab efficacy in hospitalized patients with severe COVID-19 pneumonia: a post-hoc analysis of the COVACTA trial
Abstract Background Our aim in this work is to find biomarkers to optimize therapy with IL-6 inhibitors, as not all clinical trials have shown clear benefits on mortality or mechanical ventilation progression. Given the link between delayed seroconversion and higher complication risks, we aim to tes...
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| Main Authors: | José Aguareles, Carles Forné, Ana García-Casas, Guillermo Santamaría-Corral, Daniel Carnevali-Ruiz, Gabriel Sotres-Fernández, Javier T Solera, Pablo Guisado-Vasco |
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| Format: | Article |
| Language: | English |
| Published: |
BMC
2025-05-01
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| Series: | BMC Infectious Diseases |
| Subjects: | |
| Online Access: | https://doi.org/10.1186/s12879-025-11001-6 |
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